LOCUS       NC_007617              14159 bp    DNA     circular BCT 09-DEC-2007
DEFINITION  Nitrosospira multiformis ATCC 25196 plasmid 3, complete sequence.
ACCESSION   NC_007617
VERSION     NC_007617.1  GI:82703928
KEYWORDS    .
SOURCE      Nitrosospira multiformis ATCC 25196
  ORGANISM  Nitrosospira multiformis ATCC 25196
            Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
            Nitrosomonadaceae; Nitrosospira.
REFERENCE   1  (bases 1 to 14159)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Detter,J.C.,
            Glavina,T., Hammon,N., Israni,S., Pitluck,S., Chain,P.,
            Malfatti,S., Shin,M., Vergez,L., Schmutz,J., Larimer,F., Land,M.,
            Hauser,L., Kyrpides,N., Lykidis,A. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Plasmid 3 of Nitrosospira multiformis ATCC
            25196
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 14159)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-NOV-2005) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 14159)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Detter,J.C.,
            Glavina,T., Hammon,N., Israni,S., Pitluck,S., Chain,P.,
            Malfatti,S., Shin,M., Vergez,L., Schmutz,J., Larimer,F., Land,M.,
            Hauser,L., Lykidis,A. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2005) US DOE Joint Genome Institute, 2800
            Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CP000106.
            URL -- http://www.jgi.doe.gov
            Source DNA available from Dan Arp (arpd@bcc.orst.edu)
            Bacteria available from ATCC: ATCC 25196
            Whole genome sequencing and draft assembly at JGI-PGF
            Finishing done by JGI-LLNL
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Contacts: Paul Richardson (microbes@cuba.jgi-psf.org)
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..14159
                     /organism="Nitrosospira multiformis ATCC 25196"
                     /mol_type="genomic DNA"
                     /strain="ATCC 25196"
                     /db_xref="ATCC:25196"
                     /db_xref="taxon:323848"
                     /plasmid="3"
     gene            890..1444
                     /locus_tag="Nmul_D2813"
                     /db_xref="GeneID:3786796"
     CDS             890..1444
                     /locus_tag="Nmul_D2813"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="Resolvase-like"
                     /protein_id="YP_413492.1"
                     /db_xref="InterPro:IPR006118"
                     /db_xref="InterPro:IPR006119"
                     /db_xref="InterPro:IPR006120"
                     /db_xref="GI:82703929"
                     /db_xref="GeneID:3786796"
                     /translation="MKIGYARVSTDDQNLDLQLDALTKAGCEQVFTDHGVSGATIERE
                     GLSQAIAAVGKGDVLVVWKLDRLGRSLSFLIELIEKLRNEGAGFESLSDGIDTTTAGG
                     KLVFHIMGALAEFERSLISERSKAGMQAARRRGKHIGRPHKLSREQISHAAQMIQEGR
                     ETVSGMAGLLSVDRATLYRALNRK"
     gene            complement(1517..1858)
                     /locus_tag="Nmul_D2814"
                     /db_xref="GeneID:3786797"
     CDS             complement(1517..1858)
                     /locus_tag="Nmul_D2814"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="transcriptional regulator, XRE family"
                     /protein_id="YP_413493.1"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="GI:82703930"
                     /db_xref="GeneID:3786797"
                     /translation="MKKQKRIVEGIEAETSSGNIFADLGLPNAEKLKIKSALVIEITR
                     AVRKRGLTQEEASRRMGIPQPKVSALLRGDFTGLSERKLMDCLNRLGYDIEIKVKPTT
                     EPVGHLTLAIA"
     gene            complement(1833..2219)
                     /locus_tag="Nmul_D2815"
                     /db_xref="GeneID:3786798"
     CDS             complement(1833..2219)
                     /locus_tag="Nmul_D2815"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="Protein of unknown function DUF891"
                     /protein_id="YP_413494.1"
                     /db_xref="InterPro:IPR009241"
                     /db_xref="GI:82703931"
                     /db_xref="GeneID:3786798"
                     /translation="MTDEEEKSLVWIGSSKKDLMVFPTKVRKFFGHALDFAQHGDRHG
                     AAKVLKGFSGAGVLEVVEDDAGGTYRAVYTVKFEEAVFVLHCFQKKSKSGITTPKEDI
                     DIIRARLKVAEALAKELRHEKAKAHR"
     gene            2376..3008
                     /locus_tag="Nmul_D2816"
                     /db_xref="GeneID:3786799"
     CDS             2376..3008
                     /locus_tag="Nmul_D2816"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="plasmid partition protein ParA-like"
                     /protein_id="YP_413495.1"
                     /db_xref="GI:82703932"
                     /db_xref="GeneID:3786799"
                     /translation="MAAIVAFVSQKGGVGKSTLSRALAREVAVGGLRVKVADLDTQQG
                     TSVDWHRLRLSQGIEPIVSVEAFATAAQALEAAKGFDLLIIDGPARTSQATLDIAKAA
                     DLIVQPSGPSRDDLIPAVREFHALTKAGIPNERLAFALNRVGTSAEEVAARAYLEQAG
                     YTVLAGTLRDRPAYRQAQNTGHSITETRFAGLNERADTLIQSLIDRVTNG"
     gene            3427..4659
                     /locus_tag="Nmul_D2817"
                     /db_xref="GeneID:3786800"
     CDS             3427..4659
                     /locus_tag="Nmul_D2817"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="Plasmid replication initiator protein-like"
                     /protein_id="YP_413496.1"
                     /db_xref="GI:82703933"
                     /db_xref="GeneID:3786800"
                     /translation="MVSDKNDGPKSKVTMAYALELVEIEEQLAALERTNQRLQAMAER
                     SSNNPDLERRRNEIIDKAAPLERRRQAIIAAEEAAAEVYVMHGETRSTPNLFSDIQPE
                     LGFLADIQSEVKKVEEDRSKKRERSKLLPARYTNQDFFVADILGYSLKDDHATMEAPV
                     FSLKTQKDLTPWEWTSKDGTKHIEVSPSVKYGRATQHDKDILIFVTSQMTEALNRERP
                     DTQSRAVRFTVHNYLVATNKPTGGVEYQRLERALDRLKGTTIKTDIKTGNKRVKEAFG
                     ILDSWAIIERSSSDERMIAVEITLSKWLYNAIHAHEVLTIHPDYFRLRKPLERRLYEL
                     ARKHCGSKQSSWKIGLELLREKCGAQSHIRAFRNQVQEISNAHTLPEYHLIYEREADQ
                     VTFYVKNQQKLISSYLCR"
     gene            complement(5821..6252)
                     /locus_tag="Nmul_D2818"
                     /db_xref="GeneID:3786801"
     CDS             complement(5821..6252)
                     /locus_tag="Nmul_D2818"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_413497.1"
                     /db_xref="GI:82703934"
                     /db_xref="GeneID:3786801"
                     /translation="MQDEWLKGRLAYLRGLKHPTDHQRLLLLLADKPDRTPEDERKLL
                     ALVRAEKAAERAQKARANAARIVNAEKLATRKARDRELYNAAGLMILAGLVDSKTGMP
                     LLDRGELLGALMELSRVAPEDERKAQWKRKGDALLAEKMKG"
     gene            6452..8053
                     /locus_tag="Nmul_D2819"
                     /db_xref="GeneID:3786802"
     CDS             6452..8053
                     /locus_tag="Nmul_D2819"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="MobA/MobL protein"
                     /protein_id="YP_413498.1"
                     /db_xref="InterPro:IPR005053"
                     /db_xref="GI:82703935"
                     /db_xref="GeneID:3786802"
                     /translation="MAIARLSMKVGKAGRACPHAAYIVRAGQHARHLSRGERLEAVEA
                     GNLPAWAQHDPLLFWQMADAYERSNGTTYREMEIALPRELDAGQRAALVRAFVAQEIG
                     GRHAYQWAIHTPIAADGQAQPHVHLMFSERQVDGIERDPEQYFKRYNARNPEKGGARK
                     GYGPRAGQTLSRAERAADLKELRARWQEMANTHLEQLGHSARIDMRSHAERGTGLLPE
                     KKQLPSQWRGEGRGNIIEFRQARAALVQAHEHMQQAVPDAKAEVISLEAERERRIRDR
                     EERSQAERLRIERMTSRELKAEIERLRPLSIKAAVDRHPEVMAARKIHASLSYQMRQA
                     QEKMQRATLQMHDWRRAHPLRARTHDLGLIPSSYLIEREQTREEARLRAEDLKPGVDD
                     ARRRAEDIAADIGQRMEIEQKPVREQVAKLERIWQQKANQELEVLRQAKKLDWAISEF
                     KSHAISRALKVPSYSDTGTQWKALPESAREAIDRFNTLPKDERARELERMREYFRQQG
                     PKAVEGLVQEMSQGKSRNRGQGWEL"
     gene            complement(8117..9061)
                     /locus_tag="Nmul_D2825"
                     /db_xref="GeneID:3786808"
     CDS             complement(8117..9061)
                     /locus_tag="Nmul_D2825"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="Peptidase S1 and S6, chymotrypsin/Hap"
                     /protein_id="YP_413499.1"
                     /db_xref="InterPro:IPR001254"
                     /db_xref="InterPro:IPR001314"
                     /db_xref="GI:82703941"
                     /db_xref="GeneID:3786808"
                     /translation="MENKMNQRFGCTSAGCTGKEESFDPMEAHRRLADKFNALGSLLT
                     SYMNEAPLDRALRNNHAIQLALATARIIGGTPVSKGEYKDCCLIGESLPNGIVQWNCT
                     GVLVHPQIVLTAAHCHQPPRVTASVVALSCESMNHLKDAEVIPAKISVAHPKYLQTGL
                     HDISVIILKKPATTPPCPLATTNELKSSQQLSLVGFGNSDVYSTRGFGEKRHVQVDII
                     GIRKDPNDDLDALEIKYGFESDVEILAGGLGFDSCNGDSGGPAYIDLGPQRKVAALTS
                     RAFRGASKPCGDGGIYTRTDVELDFISHVAGSYSISLN"
     gene            complement(9505..10194)
                     /locus_tag="Nmul_D2826"
                     /db_xref="GeneID:3786809"
     CDS             complement(9505..10194)
                     /locus_tag="Nmul_D2826"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_413500.1"
                     /db_xref="GI:82703942"
                     /db_xref="GeneID:3786809"
                     /translation="MARFMGSTSKEKKKKAISTAGKKLDEVVTNLVLLEFQSSVTTAQ
                     SGPVAGDSLGLIQNGDSTLSPEVVAQIHANFLDDDASGTLIDACVVALDRNRTGGAPD
                     EELAKLISKTRAKVLDQIAEVERNRNQRSNQTSNQTELASAKKQLEYLVSLQPPSLGS
                     ICASMLKNDDLQNNFLLKLQEHKLHGRIMRAKLLTKQTLLRNCFESTKDIEDKLVRID
                     KYMVCVSKELK"
     gene            10236..10499
                     /locus_tag="Nmul_D2820"
                     /db_xref="GeneID:3786803"
     CDS             10236..10499
                     /locus_tag="Nmul_D2820"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="Transposase IS3/IS911"
                     /protein_id="YP_413501.1"
                     /db_xref="InterPro:IPR002514"
                     /db_xref="GI:82703936"
                     /db_xref="GeneID:3786803"
                     /translation="MKKRFTDEQIIGFLKQADGGIPVRELCRQHGFSDASFYTWRARF
                     GGMTVSDARRLRDLEAENAQLKKLLAESLLDAQALKVALGRKH"
     gene            10526..11356
                     /locus_tag="Nmul_D2821"
                     /db_xref="GeneID:3786804"
     CDS             10526..11356
                     /locus_tag="Nmul_D2821"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="Integrase, catalytic region"
                     /protein_id="YP_413502.1"
                     /db_xref="InterPro:IPR001584"
                     /db_xref="GI:82703937"
                     /db_xref="GeneID:3786804"
                     /translation="MAMLEQTNVSERRACLLVDISRTVLHYMSKVRLENEQLQGRMVE
                     LASERRRFGYRRIHALLRREGVEANHKRIFRLYQAAGLAVKRRRRRGGVAVEREQLAL
                     PSQPNEVWSMDFICDALANGRRIKVLTIVDDFTKESIDLVAEHGISGQHVVRVLEQAS
                     QFRGLPLAIRTDQGPEFTSKALDQWAYKHGVQLKLIEAGKPTQNAYIESFNGRFRDEC
                     LNDHWFTSLAEARIRISAWRRDYNEHRPHSALNYLTPAEFAANCRRQEEINGCERNGS
                     "
     gene            complement(11394..12149)
                     /locus_tag="Nmul_D2827"
                     /db_xref="GeneID:3786810"
     CDS             complement(11394..12149)
                     /locus_tag="Nmul_D2827"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_413503.1"
                     /db_xref="GI:82703943"
                     /db_xref="GeneID:3786810"
                     /translation="MKIGLIICLVPLLSTGCAFLDRQERRINYTEALDSNNTPGGNPS
                     LITDAKQRAIINTKADVGIRRSSGKSDGSSDTSSANTDHVIKNHPTRIICAEPSPDVA
                     QAISAAFTAAAKVDIKASEIKNISGSGSVGSSYASSIAQLGARLSTVQLLRDKMYRAC
                     EAFQNGAISDTSYTLMLARFDKTMASMLASEIAAGAFGQKLAALGSSASTKGTDPKKL
                     DEARVAVKDASQQLQEAVELPETDDQAKVMCPR"
     sig_peptide     complement(12087..12149)
                     /locus_tag="Nmul_D2827"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 2.0 HMM (Signal peptide
                     probability 0.718) with cleavage site probability 0.699 at
                     residue 21"
     gene            12615..12950
                     /locus_tag="Nmul_D2824"
                     /db_xref="GeneID:3786807"
     CDS             12615..12950
                     /locus_tag="Nmul_D2824"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="transcriptional regulator, XRE family"
                     /protein_id="YP_413504.1"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="GI:82703940"
                     /db_xref="GeneID:3786807"
                     /translation="MTTIRQDHVTFGSYIAEARKKLSMSQKELAARILREEDGQPISP
                     QYLNDIERDRRSPTSDHLIQQFAKVLQIDADYLHYLSGKLPEEIRQRNLSQDDVKAAF
                     MAFRKPNKK"
     gene            12958..13674
                     /locus_tag="Nmul_D2822"
                     /db_xref="GeneID:3786805"
     CDS             12958..13674
                     /locus_tag="Nmul_D2822"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_413505.1"
                     /db_xref="GI:82703938"
                     /db_xref="GeneID:3786805"
                     /translation="MVAYIRDLTGRFQQRPHYKPEELDRECESIITGFLKSLYGNVRY
                     PVETEDLKKLIERDADDLDVYADLSIYGAEVEGVTEFYPGRKPIVRIAAELTEDERRE
                     NRLRTTLTHEYGHVHFHAYLWEMEPLQADLLRRQPNRDKIICKRDTMIDATHTDWMEW
                     QAGYVCGAILMPKTAVVGLCRSFVEQRGLYSAVSTRTYHGQDLIASVISSFQVSEDAA
                     RVRLIKLGLLTESVSTPSLF"
     gene            13799..14086
                     /locus_tag="Nmul_D2823"
                     /db_xref="GeneID:3786806"
     CDS             13799..14086
                     /locus_tag="Nmul_D2823"
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_413506.1"
                     /db_xref="GI:82703939"
                     /db_xref="GeneID:3786806"
                     /translation="MATKHEVKCINKTDRPNPHERIRAIGGVNADGTNWKLSQQDAIR
                     GIEDGKWSFYVSVRGQIVNVIIGISRYGNKYLKTEADGEQPNNLLSLYECA"
ORIGIN      
        1 catccttcga cagtaatttt tatattcgat ggatcaacac caaatgtcat tgcgaggcga
       61 cgcttcgctt cgctgatggt aagagtctca tcatcagcgt tcaattcgtt gatcttgcta
      121 gcagtcaact gcttatctga tacctggacc tgctctaaag gtactcttgc gatttcggtg
      181 cctattcctg cacctccgcc gacatgagtt acaggattct ctgcatcagg ctcataaaga
      241 ggcagccata tcccttgtcc catcggaaga gaataacctg ctgcacgacg cgcggcgaaa
      301 gcccgatcaa aacgctcccg caaatcatca ccttcaatca tatgaactcg cgcgagttct
      361 gaattatcag gatcaacaga aatcacgatt accttgtcaa catcagaaag agtggtccac
      421 tgtttgttac cctccggagg aaaggcaatc caagtgtctt gggttgtccg aatgctagtg
      481 atgtagcttt tcttgccttt cgtgatacgc ctgacactac cctttccaat ttttggaatt
      541 cgctcaacgg tccagccatc accctctagt gtttcaacgc caatctggaa cagacgtctc
      601 cttattaaag ttctttttgt attatcgaaa gtatcctctg aagtattttc cattttgttt
      661 aaaacaatta agtaataacg tagtaaatat attttattcc tataataaac gcaatagttt
      721 ttttaatttt ttagtattta ctataaatac tgattactgg tagctaactt atcgttagtg
      781 aggcaaaatg ggtccctttt gctacactca aacacacaat gcaaggcatt gttttttttg
      841 gcctctgctg ttgcataagg gttgtgcgaa ataaaggggg aagaaattca tgaaaatcgg
      901 ctatgcgcgg gtttccaccg atgaccagaa tcttgacctg cagctggacg ctttaaccaa
      961 ggcgggatgc gagcaggtat ttaccgatca cggcgtcagc ggagccacca tcgagcgtga
     1021 aggactgtcc caggcaattg ccgcagtcgg gaaaggcgat gtgctggttg tgtggaagct
     1081 ggaccgtctg ggccggtctt tgagttttct gattgagctg atagagaagc tgcgaaacga
     1141 aggcgccggc ttcgagagcc tgtcggatgg gatcgacacc acgactgctg ggggtaagct
     1201 ggtatttcac atcatgggtg cgttggcgga atttgagcgc tcattgatat ctgagcgctc
     1261 gaaggccggg atgcaggcag ccaggcggcg aggaaagcat ataggccgtc cacacaagtt
     1321 gagccgggag cagatcagcc atgcagctca gatgatccag gagggacggg aaaccgtatc
     1381 cggcatggcc gggctgctga gtgtggatcg agctacttta taccgtgcat tgaatcgaaa
     1441 gtaagttatt tgataaccgt gatcatcgca ccggattgct gcaacgcaag gccagcagca
     1501 gaggtggtcc tcgtccttaa gcgatagcca gcgtcaagtg cccgactggc tcggttgttg
     1561 gctttacctt gatttcgatg tcatacccca ggcgattcaa gcagtccatc agcttacgct
     1621 cggacaaacc ggtgaagtcg ccacgcagta gcgcagatac tttaggttgc ggaatgccca
     1681 tccgacggct ggcctcttct tgagtcagac cacgtttacg cacagctcgg gtgatttcga
     1741 tcaccagggc agacttgatc ttgagttttt cggcattcgg caagcccaga tcggcaaaaa
     1801 tgttgccgga actggtctca gcctcaatgc cttcaacgat gcgcttttgc tttttcatgt
     1861 cgtagctcct ttgcaagtgc ctcggccacc ttcagtctgg cgcggataat atctatgtcc
     1921 tccttcggcg ttgtgattcc gctcttgctc ttcttctgga agcagtgcag gacgaacacg
     1981 gcttcctcga atttcacggt atagacagcg cgataagtcc cacccgcatc atcttcgact
     2041 acttccaaga caccagcgcc actgaagccc ttgagcactt tggccgcgcc gtgtcgatca
     2101 ccgtgctgtg cgaaatccag ggcgtgaccg aaaaatttgc gtaccttggt cggaaacacc
     2161 atcagatctt tcttactgct cccgatccag acgagtgatt tttcttcttc atcagtcata
     2221 gcatattata ccaaaatagg tataaaaagt aatcgtagtg tagggcctta caatcgaatg
     2281 cttggttcat ttgtaatgaa ttaaattcta gcagctagac tatatctagc agctagaata
     2341 aaatatttat ttctagctgc tagataggag tttttatggc cgcaattgtt gcattcgttt
     2401 cccaaaaagg tggggttggg aaaagtactc tctcccgcgc gttagcgcgt gaagtcgcgg
     2461 taggtggttt acgggtaaaa gttgcagact tggatactca gcaaggaaca tcagttgatt
     2521 ggcatcgtct acgattatcc caagggattg agccaatcgt atcagtagag gcatttgcca
     2581 ccgctgcaca agcgcttgaa gctgcaaaag gttttgattt acttatcatt gatgggccag
     2641 cccgcactag tcaagccaca cttgatattg ccaaggcggc cgatttgatt gtgcagccat
     2701 caggcccgtc gcgggatgat ctaatcccgg cagtacgtga attccacgca ttgacgaaag
     2761 ctggcatccc gaatgagcgc cttgcgttcg ccttgaatcg agttggtact tccgctgagg
     2821 aagtggcggc acgagcctac ttggaacaag ctggatatac ggtcttagcc ggtaccttgc
     2881 gtgatagacc agcttaccgg caagcacaaa acacaggtca cagcattacc gaaaccagat
     2941 ttgcaggact gaatgaacgc gccgatactc tgattcaatc gcttattgac cgggtgacta
     3001 atggctgatg tatcgaaact caagacgcta aaaggacgtc gctcaaactt aggcgacccc
     3061 ccatctttgg atgaagccag caataatctg aacgcaccag agattgcacc ggcgccttcc
     3121 ctgtcttcaa aagcactagg gggaaagatt gacggtcgta ctgctcgccg tacgaacaga
     3181 accgtccaat ttgctacccg tgttacccca gactgggatg cgcgtatcag ggctatagct
     3241 gaccgcgaag ggataaaact ggttgaagtt ttggaaaggg cgctagatta ctatgaatta
     3301 aaatctagcc gatagatagc agctagataa aaactagcag ctagattggt aatttgcatc
     3361 atctatgatt gagaagaaca ttccactcaa gcatgagcaa tcatattaat cactaactga
     3421 gtaactatgg tatctgacaa gaacgatggg ccaaaatcca aagtaactat ggcttatgcc
     3481 ttggaattgg tagagatcga ggagcaattg gcagcgctgg agcgtacgaa tcaacgtctc
     3541 caagcaatgg ccgagcgatc ctcgaacaat cctgatcttg agcgccgcag aaatgaaatt
     3601 atcgacaaag cagctccgtt agaacgacgt agacaagcaa tcattgctgc ggaagaggct
     3661 gccgcggaag tttatgtcat gcacggagaa actagatcta ctcctaactt atttagcgac
     3721 attcagcctg aattaggttt cttggccgat attcagagcg aggtcaaaaa agtcgaagag
     3781 gataggagca aaaagcggga acgatccaag ctactgccag ctcgttacac aaatcaggat
     3841 ttctttgttg cagatatcct cggctattcg ctcaaggacg accacgccac aatggaggcc
     3901 cccgtttttt cacttaagac tcagaaagat ctcactcctt gggaatggac aagtaaagac
     3961 ggtacaaagc acatcgaggt atcgccttcg gtcaaatatg ggcgagctac ccagcatgac
     4021 aaggatattt tgatctttgt tacctcgcaa atgacggaag ccctgaatcg tgagcggcca
     4081 gacacccaaa gtcgggccgt gcgttttacc gtacataatt atctcgtggc aaccaacaaa
     4141 cctacagggg gggtggaata tcaacgactt gaacgagcac tggatagact caagggaaca
     4201 acgattaaaa ccgacatcaa gactggtaac aagcgcgtta aagaagcatt tggcattctc
     4261 gattcttggg caatcattga gcgttcgtca agtgatgaac gcatgattgc tgttgaaatc
     4321 accttatcca agtggcttta taacgcaatc cacgcacacg aagtgctaac gatccatcct
     4381 gactattttc ggttacgcaa acccttggag aggcgtttat acgagttagc cagaaagcac
     4441 tgtggcagca agcagtcaag ctggaaaatc ggacttgaat tactacggga gaagtgtggg
     4501 gcgcagagtc acatccgcgc cttccgaaat caggtacagg agatcagtaa tgctcataca
     4561 ctgcctgaat accacttgat ctacgagcgg gaagcagatc aagttacttt ctacgttaaa
     4621 aatcaacaga agctcatctc ttcttattta tgtcgctgac gcttaattcg ttatatcgct
     4681 gacattgtgg attgactcgt tatatcgctg acactttcct gtggattgac tcgttatatc
     4741 gctgacgcgt gactcgttat atcgctgaca ctctattcgc aaagcactat actttacagt
     4801 cacttaatag gtatatttcc taccgtaaca cgcgcgcgtt ttttaactta taaaatcttt
     4861 aacacctcgc cccccactcc agctgtggat aacacatctc cagcaattaa attcccaatt
     4921 taaaggaatt tatcgacgcc ccctgaaggg ggccaaaaga cccccttcca gtttcacctt
     4981 ttgtactttg cccgcttgtg tttctcatct ttttcaaaag atacaaaagc catcttccga
     5041 accttaagca gagcatgagg gcaatccagg tggctcagct gccatagttc cttagcagct
     5101 gacctgagcc ttacggctca ccctcatggg caccaggacc cggacaaatc agccccagcc
     5161 tgcaagcagg ctgggagctt cagccgggtt tctgtggaaa ttgccctttg tccattcagc
     5221 tatcccttgc acgtcctcaa aacctgtctt caggaggaag gggcaaggtg gagctgggat
     5281 tcatgcagaa atacccttca gatgcgttct caaggctgtg gagcgcattt ctacctcaag
     5341 ctgaaggaaa tctatctctt ttcctattaa acgctccaaa gggctttaaa agcctttttg
     5401 tgaaagacac tttcctggaa cagctgtttt cgccttcaag gcagggtcaa ggcgggtgcc
     5461 aagccccccg agagggcatg gccttgaggc tgcctgaagc gacacacgct aagaccaggg
     5521 gtgcagggag ggtttgaccg caggtctccc tgcacccctg ccccgtggcg aacgcggggc
     5581 gtggggcagc gccccaggta cttgcgcagc aattgcaaca aaccagaaaa ttcctgcatg
     5641 aaccctgtat ttatttgcag cacccgatat tctttttgga atgtttcgat atttttttga
     5701 agtaaccgat atttttcaga agtgctcgat atatttctgt taaaaagttg acgggttatc
     5761 cagcaccctc ccttgatcag gaatttggcg ctgacagggc ttgagcactc ctgctgaccg
     5821 tcaacccttc attttttctg ccagcagggc atcgcccttg cgcttccact gtgctttgcg
     5881 ctcatcctca ggggctaccc tggagagttc catgagcgcg cccaggagct ctccccgatc
     5941 caggagcggc ataccggttt ttgaatccac caggcctgcc aggatcatca ggcctgcggc
     6001 gttatagagc tcgcggtcgc gtgcttttcg tgttgcgagc ttttccgcat tcacgatcct
     6061 ggcggcattg gcccgtgcct tctgtgcacg ttccgctgct ttttccgcgc gcacgagtgc
     6121 cagaagtttg cgttcatcct ctggcgtcct gtccggcttg tctgccagca gcagcaatag
     6181 ccgctggtgg tcagtggggt gtttgagtcc ccgcaagtaa gccagccgtc ccttgagcca
     6241 ttcgtcctgc atggggcctc ctcattgttg agaaccagtc gattgtagcg gaaaacttgg
     6301 cagcaggcac agactgaagt atccttgtaa tacacaaggc gcgcttagtt gtttctttgg
     6361 atggtaagac cctcatccat agaaacacgc gaacaagaaa agcaaagatc aggccgcttc
     6421 gcggccaaac aaacaatgga gaacacccgg catggcaatc gcgcgcctga gcatgaaagt
     6481 ggggaaagcg ggccgagcgt gcccgcatgc tgcctacatc gtgcgcgcgg ggcagcatgc
     6541 ccggcatctt tcccggggcg agaggctcga agcggttgaa gcgggcaacc tgccggcctg
     6601 ggcgcaacat gatccgctgc ttttctggca gatggcggat gcttatgagc gcagcaacgg
     6661 taccacctac cgggagatgg agattgccct gccaagggaa ctcgatgccg ggcagcgggc
     6721 agcgctggtg cgggcattcg tcgcccagga gatcggaggc cgtcacgcgt accagtgggc
     6781 catccacacc cctatcgcag cggatggcca agcgcagccg cacgtccacc tcatgttctc
     6841 cgagcgacag gtggatggca ttgagcgcga cccggaacag tacttcaagc gctacaacgc
     6901 caggaatccg gagaagggcg gggcgcgcaa gggctatggg ccgcgtgcgg gccagaccct
     6961 gagccgggcc gagcgcgcag cggatctgaa ggaattgagg gcccgctggc aggagatggc
     7021 caatacccat cttgagcagc tggggcacag cgcgcgcatc gacatgcgca gccatgcaga
     7081 gcgcggtaca ggtcttcttc ctgagaagaa gcagctgccg agccagtggc ggggggaagg
     7141 gcgagggaac atcatcgaat tccgccaggc gcgggcggcg ctcgtgcaag cccatgagca
     7201 tatgcagcag gcggtacccg atgcgaaggc cgaagtcatc agcctggaag ctgagcggga
     7261 gcgacggata cgggatcggg aggagcggag ccaggcggag aggctgcgca tcgagcgcat
     7321 gacgagccgc gagctcaaag ccgagatcga gcggctgcgg ccgctatcaa tcaaagccgc
     7381 ggttgatcgt cacccggagg tgatggctgc gcgaaagatc catgcctccc tgtcgtatca
     7441 gatgcggcag gcgcaggaaa agatgcagcg ggccacgctg caaatgcacg actggcgcag
     7501 agcccatccg ctacgggcca ggacgcacga cctgggactg atcccatcca gttacctcat
     7561 cgagcgcgag cagaccaggg aagaagcccg gttgcgggct gaggatctta agcccggggt
     7621 cgacgatgcg agaaggcggg ccgaggatat tgccgccgac atcggacagc gcatggagat
     7681 cgaacagaag ccagtgcgcg agcaggtggc caagcttgag cgcatctggc agcagaaggc
     7741 taaccaggag ttggaggtgc tgcggcaagc aaagaaacta gactgggcca tatcagagtt
     7801 caagagccac gccatcagcc gtgcactgaa agttcccagt tacagcgaca ccggcacaca
     7861 gtggaaagcg ctgccggaga gcgcacgtga agcgatagac cggttcaata cccttccaaa
     7921 ggacgaacgg gcgcgggagc tggaaaggat gcgggagtat ttcaggcagc aggggccgaa
     7981 agctgtggag ggactggtgc aggaaatgag tcaggggaaa agcaggaata ggggtcaggg
     8041 atgggagctt tgagcatgat aaaatcatgg aagttgctga acgactacag cgcgttaaac
     8101 tgggggagat tcagtatcag ttaagagaaa tgctgtaaga accagcaaca tgactaataa
     8161 aatcgagctc tacatctgtg cgggtataaa tcccaccatc tccacatggc ttactagcac
     8221 cacgaaacgc cctagaggtg agggcagcaa ctttcctttg agggcctagg tctatatagg
     8281 cgggaccgcc actatcccca ttacaactat cgaaaccaag gcctccagca aggatttcaa
     8341 catcagattc aaatccatac ttgatttcga gagcgtctaa atcatcatta ggatcttttc
     8401 taatgccaat tatgtctact tgcacatgcc ttttttcccc aaatcctctc gtgctataga
     8461 catctgagtt tccaaaacct actagtgaaa gttgttgaga ggatttcaat tcattggtag
     8521 tagctaaagg acagggggga gttgtggcag gtttttttag gattattact gatatatcat
     8581 gaagccctgt ttgaagatac tttggatggg caacactaat ttttgcaggg attacttctg
     8641 catcttttaa atggttcatg ctttcgcatg acaaagcaac aactgaagcc gtaactcttg
     8701 gtggttgatg acaatgggca gctgtaagaa cgatttgggg atgtacgagt accccggtac
     8761 agttccattg aactattccg tttggcagtg actctcctat aagacaacaa tctttatatt
     8821 ctcctttgct tacaggtgta ccaccgataa tacgtgcagt tgccagagcc agctgaatag
     8881 catgattatt tctaagggct cgatctaagg gggcttcgtt catataggaa gtcaaaaggc
     8941 ttcctagagc attaaattta tcagccaatc ttctgtgagc ttccattgga tcaaaagact
     9001 cctcttttcc agtacaacct gcactggtgc agccaaaacg ctggttcatc ttattctcca
     9061 attgttattg tcttccaggg gatggtgcta ataagcccac tagaccgccg acagctgctg
     9121 ttgatagggg aagcagaagc tttatgaatt cttctgaagc aaacattgcg agaggaaaaa
     9181 tgaggattat ggcagcgctc aatgcgctta cgactatcct atatatccat ttatcggttt
     9241 ctagagggga tttaagctcc tcaatcttct caagaattgg ctttttttct tgagcgtcaa
     9301 taggagattc ctctacgagt gctcggattc tatcaagttg ttgaatatcc ctgttcattt
     9361 ggcattaact cccgttaatt caatggtttt atttttattt atagatgaaa gaataggcaa
     9421 agtaagaaaa atgcatgtcc gacagcaaaa ttttccattt tagagcggca ctgattctga
     9481 ttcgggtcgc tactatggga cacatcactt taattccttc gaaacacaaa ccatatactt
     9541 gtctatccgc acaagtttgt cttcaatatc tttcgttgac tcaaagcaat ttcttaaaag
     9601 agtctgctta gttagaagct tagctctcat aatgcggcca tgcaatttat gctcctgcag
     9661 ctttaataga aagttgtttt ggagatcgtc atttttgagc atagatgcac atatactccc
     9721 caaagaaggg ggttgtaagc ttaccaagta ctcaagctgt ttcttggccg atgcaagctc
     9781 ggtttgatta ctggtttgat tactgcgctg gttcctattc ctttctactt cagctatctg
     9841 gtcgagtacc ttagcgcggg ttttgcttat tagcttagcg agctcctcat ctggagctcc
     9901 acccgttctg ttccgatcta gcgctacaac gcaggcatca ataagggttc ccgaggcgtc
     9961 atcgtcaaga aaattagcat gaatttgagc taccacttcc ggggagaggg tggaatctcc
    10021 attctgaatt aagccaagtg agtcacctgc aaccggccca gactgagctg tcgtaactga
    10081 agattggaac tcaagcaata ctagattagt tacaacttca tcgagctttt tgccagcagt
    10141 tgaaatagct ttcttttttt tctcctttga tgtgctcccc ataaaacgtg ccatctggaa
    10201 tctagtaaag ttcgtttttc gagaggagaa cggacgtgaa gaagcgattt acggatgaac
    10261 aaattattgg atttctgaag caggcagatg gaggcattcc ggtcagggaa ttgtgccgcc
    10321 agcatggttt ttccgatgcg tcgttttaca cctggcgtgc caggtttggt gggatgacag
    10381 tatcggatgc caggcggttg cgagatcttg aagcagagaa tgctcagctc aagaagcttt
    10441 tagccgagtc gcttcttgat gctcaagcct tgaaggttgc tttgggccga aagcattaac
    10501 tccacaggcc aggcgtgagg cagtaatggc gatgcttgag cagacgaacg tttccgaacg
    10561 ccgtgcctgc ctgcttgtgg atatatcacg tacggtattg cactacatgt ccaaggtgcg
    10621 gctggagaat gagcaactgc aaggtcgaat ggttgagttg gcctctgaac gccgtcgttt
    10681 tggttatcga cgcattcatg ccctgctgcg gcgtgagggt gttgaagcca atcacaaacg
    10741 catctttcgc ctttaccagg ctgccgggtt ggcagtaaag cgccgacgca ggcgaggggg
    10801 cgtagcagtt gaacgtgagc aattggcatt gccaagccag cccaacgagg tatggtcaat
    10861 ggatttcatc tgtgatgcac tggcgaatgg cagacgcatc aaggtattga ccatcgttga
    10921 tgacttcacc aaggaatcca ttgatctggt agctgaacat ggcatttcgg gacaacatgt
    10981 cgtgcgcgta ttggagcaag cttcacagtt tcgtgggttg cccttggcca ttcgcaccga
    11041 tcagggaccg gagttcacca gcaaggcact ggatcagtgg gcttataagc atggtgtcca
    11101 gctcaaattg attgaggcgg gcaagccgac gcaaaatgca tatattgaga gcttcaacgg
    11161 tcggtttcgg gatgagtgcc tgaacgatca ctggtttacc agcctggctg aggcacggat
    11221 tcggatatca gcctggcggc gcgactacaa cgagcatcga ccgcacagtg cactaaatta
    11281 cctaaccccg gcagaatttg cagccaactg ccgcaggcaa gaagaaataa acggctgtga
    11341 aagaaatgga agctaattta taactgaact ttgctagaac gcccctggca ctactaccgg
    11401 gggcacatca ccttagcttg atcatcggtt tctggtagct cgaccgcctc ttgcagttgc
    11461 tgtgatgcgt ccttaactgc aacacgtgct tcatctagtt tctttggatc cgtgcctttt
    11521 gtggaggcgc tgctacctag agcagcaagt ttttgcccaa atgctccagc agcaatttca
    11581 gaggccaaca tgctagccat tgtcttgtcg aaacgcgcta gcatgagcgt atagctcgtg
    11641 tcactaatgg caccgttttg gaaggcttcg caagcgcgat acattttgtc ccgcagcaat
    11701 tgcaccgtcg atagtcgcgc tcccaattgg gcgatgcttg atgcgtagga cgatccaact
    11761 gatcccgatc cgctaatgtt ctttatttcc gaggccttta tgtcaacctt tgcagcagca
    11821 gtgaaggcag ctgatattgc ttgagcaacg tcaggactag gttcggcaca aatgatacgg
    11881 gtagggtgat ttttaattac atgatcggtg ttggctgaag aggtatcact tgaaccatca
    11941 cttttaccgc tagatctcct aatgccgaca tctgcttttg tgttaatgat ggcacgttgt
    12001 ttagcatctg tgattagaga tggattaccg cccggcgtat tgttagaatc gagggcttcc
    12061 gtatagttaa tgcgtcgttc ttgtcgatcc aaaaatgcgc atcctgtaga caaaagcgga
    12121 actaagcaga taattagacc tattttcatt attagaacct caattataga gagagggatt
    12181 aatcagtctt cttggaatta gcaacagtgc agattgtgaa ttccgatcca tcatcgaccc
    12241 gcatcacttt tttcgtaaaa attctttctt gcgaccccca ttaaaattaa attagcaata
    12301 tccttctgaa ggattcaatt cttatatttc cttttaaatt cataccctga tagtcttatt
    12361 tataggtttt ttggctttat tttgcttgtt atttatcgtt tcgtttatag taacgggcat
    12421 tgcaaaaagt cttcccttca ctacacaaat ctagagcatg tgcaaagcag ggatataaga
    12481 ctaccgtttg taaagaccgc gccctacctc ctgctggtgc tggttgtgtc agccccgctt
    12541 tcgaactctg ctactcaaat tgacgaaagt gtctatagtg gtatacgcta ataagcggag
    12601 gagcggaaat tattatgact acgatacgac aagaccatgt tacttttggt agctacattg
    12661 cggaagcgcg caagaagcta tcgatgagcc agaaggagct ggcggcccgt atcctacggg
    12721 aagaagatgg acagcccatc tctccccaat atctcaatga tatcgaacgc gaccgccgga
    12781 gccccacatc cgatcattta atccagcagt tcgcaaaggt tctccagata gatgcggatt
    12841 acctgcacta cctctctggt aaattacccg aggaaatcag gcagcggaat ctttcccaag
    12901 atgatgtgaa agccgctttc atggccttcc gtaaacccaa taaaaaataa taatttcatg
    12961 gttgcttaca tacgcgacct gactggtcgt tttcagcagc gtccccacta taaacccgag
    13021 gaactggatc gcgaatgcga atccatcatc acgggctttc tcaaaagtct ctacggtaat
    13081 gttcgctatc cggtcgaaac agaagatctg aaaaaattga tcgagcggga tgcggatgat
    13141 cttgatgtat acgccgacct ttcaatttac ggtgcggaag tggagggagt tacagagttc
    13201 tatcctggcc gtaaaccaat agtccggatc gcggcagagc tgactgagga tgagcgccgg
    13261 gagaaccgat tgcgaacaac cttgacccat gaatatggcc atgtccactt tcatgcttac
    13321 ctctgggaaa tggagcctct gcaggcggac ttgcttcggc ggcaacctaa tcgcgataag
    13381 atcatctgca agcgcgacac gatgatcgac gcgacccata cggactggat ggagtggcag
    13441 gccggttatg tttgcggagc gattctgatg cctaaaacgg ccgtagtagg gctatgccgt
    13501 tcgtttgtcg aacagcgtgg tttatatagt gcggtttcaa cccgaacgta tcacggtcag
    13561 gacctgattg ctagcgttat cagttctttc caggtatcgg aagacgcagc ccgcgtacgc
    13621 cttataaagc tcggtctatt gactgagtct gtttctacgc catccctgtt ttaattaatt
    13681 gctcgcaaat ctattgcaga gcttacacgt actgtgatac gctaataagc gtatcggcgg
    13741 attagcggtt ttgcgatggt cgcacctcta ccccggtcat tcatatagga gatataaaat
    13801 ggcaactaag catgaagtga agtgcattaa taaaactgac cgtcctaatc ctcacgaacg
    13861 tattcgagcg attgggggag tgaatgcaga tgggacaaat tggaaattaa gccagcaaga
    13921 tgcaattcgg gggattgagg atggaaaatg gagcttttac gtatcagtac gtggccagat
    13981 cgtgaatgta attattggca ttagccgata tggtaataag tatctaaaaa cagaagctga
    14041 tggagagcag ccgaacaatc ttctttccct gtatgagtgt gcttaaccca actcaataac
    14101 gtgctaccgc tgctgatcgg gtagcggtag ctgctctaga acctctacca aaaacgtct
//
