LOCUS       NC_002253               7786 bp    DNA     circular BCT 30-NOV-2007
DEFINITION  Buchnera aphidicola str. APS (Acyrthosiphon pisum) plasmid pLeu,
            complete sequence.
ACCESSION   NC_002253
VERSION     NC_002253.1  GI:10957103
KEYWORDS    .
SOURCE      Buchnera aphidicola str. APS (Acyrthosiphon pisum)
  ORGANISM  Buchnera aphidicola str. APS (Acyrthosiphon pisum)
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
            Enterobacteriaceae; Buchnera.
REFERENCE   1  (sites)
  AUTHORS   Shigenobu,S., Watanabe,H., Hattori,M., Sakaki,Y. and Ishikawa,H.
  TITLE     Genome sequence of the endocellular bacterial symbiont of aphids
            Buchnera sp. APS
  JOURNAL   Nature 407 (6800), 81-86 (2000)
   PUBMED   10993077
REFERENCE   2  (bases 1 to 7786)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-SEP-2004) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 7786)
  CONSRTM   NCBI Microbial Genomes Annotation Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-JAN-2000) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AP001071.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..7786
                     /organism="Buchnera aphidicola str. APS (Acyrthosiphon
                     pisum)"
                     /mol_type="genomic DNA"
                     /strain="APS"
                     /isolate="Tokyo1998"
                     /specific_host="Acyrthosiphon pisum"
                     /db_xref="taxon:107806"
                     /plasmid="pLeu"
                     /note="leucine plasmid
                     primary endosymbiont of Acyrthosiphon pisum"
     gene            complement(346..1197)
                     /gene="repA1"
                     /locus_tag="BUpL01"
                     /db_xref="GeneID:1109453"
     CDS             complement(346..1197)
                     /gene="repA1"
                     /locus_tag="BUpL01"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated protein RepA1"
                     /protein_id="NP_057965.1"
                     /db_xref="GI:10957104"
                     /db_xref="GeneID:1109453"
                     /translation="MIIRKCYINNPNPFFTPPKNNKRRPSFICYAMKRASEIDVARCE
                     LNYILQIKNIKIGFPVKRFRRLNEHRACAMRAMVLAMLYHFNISSDLVQASVEQLSDE
                     CGLSTLSKAGNKSITRASRLITNFMEPMGFVTCKKTWDKILGNYMPKMITLTPLFFML
                     FGVSEKKLMDAKKQQLGWINKNLISKGFKPITMIDAKRRSKDTQIKNIFQYRISKHAF
                     YKKKRNAQRLISLDEKEARQTILRALVAKYSITELTKLGPNGLKKQVNISYYYLRKIA
                     TNTYPDN"
     gene            1514..2017
                     /gene="yqhA"
                     /locus_tag="BUpL02"
                     /db_xref="GeneID:1109454"
     CDS             1514..2017
                     /gene="yqhA"
                     /locus_tag="BUpL02"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_057966.1"
                     /db_xref="GI:10957105"
                     /db_xref="GeneID:1109454"
                     /translation="MEKIIEKSIYASRWLMFPVYVGLSFGFILLTLKFFQQIVFIMPD
                     IVAMSESGLVLVVLSLIDIALVGGLLVMVMFSGYENFISKMDIQDNQKRLGWMGTMDV
                     NSIKNKVASSIVAISSVHLLRLFMEAEKILDDKIMLCVIIHLTFVLSAFGMAYIDKMS
                     KKKHILH"
     gene            2357..2893
                     /gene="RepA2"
                     /locus_tag="BUpL03"
                     /db_xref="GeneID:1109448"
     CDS             2357..2893
                     /gene="RepA2"
                     /locus_tag="BUpL03"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated protein RepA2"
                     /protein_id="NP_057967.1"
                     /db_xref="GI:10957106"
                     /db_xref="GeneID:1109448"
                     /translation="MRAIVPAMLYYFNINSKLVEASIEKLADECGLSTLSDSGNKSIT
                     RASRLISEFLEPMGFVKCKKINSKSMSNYIPKKIFLTPMFFMLCGISPSEINHFLSKK
                     IKPLKKLKKQEKSAFISFTDMKIISQLDERSARTKILNALINYYTASELTKIGPKGLK
                     KKIDIEYSNLCNLYKKKS"
     gene            3032..4591
                     /gene="leuA"
                     /locus_tag="BUpL04"
                     /db_xref="GeneID:1109449"
     CDS             3032..4591
                     /gene="leuA"
                     /locus_tag="BUpL04"
                     /EC_number="2.3.3.13"
                     /note="catalyzes the formation of 2-isopropylmalate from
                     acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="NP_057968.1"
                     /db_xref="GI:10957107"
                     /db_xref="GeneID:1109449"
                     /translation="MKSKVVIFDTTLRDGEQALQASLSVKEKLQIALSLEKCGIDILE
                     IGFPVSSPGDFKSVQTISKNIKNSRICSLARCIEKDIDAAGEAMSSSDSFRIHIFLAT
                     STLHMESKLKKNFNEIIDMAVFSVKKALRYTDDIEFSCEDATRTTMDNLCRIVETLIK
                     SGVKTINIPDTVGYTVPNELSCIIKNLFERVPNIHKSIISVHCHDDLGMAVGNSISAI
                     QAGARQIEGTINGIGERAGNTALEEIIMAIKVREDILSVSTNINYKEIYRTSKIVSQI
                     CNMPIPSNKAIVGSNAFAHSSGIHQDGVLKNRKNYEIMEPSSIGLKEVKLNLTSRSGR
                     AAVKHYMDEMGYNNSDYNIDELYTAFLKLADKKGQVFDYDLEALAFINKQQDEWEYFS
                     LKFFSVQSISNSLSTASVKLLCGKKTYTESSTTSNGPVDAIYQALNRIACFPIILQKF
                     QLVAKGKGKDALGQVDILVEHKKRKFHGVGLATDIIEASAQAMINVLNNIWKAKQVNK
                     KLKILKDFKKK"
     gene            4652..5743
                     /gene="leuB"
                     /locus_tag="BUpL05"
                     /db_xref="GeneID:1109450"
     CDS             4652..5743
                     /gene="leuB"
                     /locus_tag="BUpL05"
                     /EC_number="1.1.1.85"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="NP_057969.1"
                     /db_xref="GI:10957108"
                     /db_xref="GeneID:1109450"
                     /translation="MKKNYRIAVLSGDGIGPEVMQEACKILNVLKKYFFLSLEIQKFN
                     IGGIAIEREGVALPKTTLLGCENSDSILLGSVGGKKWDNLPVEQRPERAALLPLRKHF
                     NLFSNLRPAKLYPELKCLSPLRSDIVKNGFDILCVRELTGGIYFGEPKGFVNKNNTKY
                     AFDTEIYHEYEIIRIAHLAFKLARSRKKKVCSIDKSNVLQSSILWREVVESVSKKYPD
                     VHLSHLYIDNAAMQIIKDPNQFDVLLCSNLFGDIISDECATITGSIGMLPSASFNEKN
                     FGLYEPAGGSAPDIEGKNIANPIAQILSLSMLVRYGMNLNQIADKIDKAVNNVLKKGY
                     RTSDISHDNNFLKTDEMGDLIVDSLINGE"
     gene            5733..7160
                     /gene="leuC"
                     /locus_tag="BUpL06"
                     /db_xref="GeneID:1109451"
     CDS             5733..7160
                     /gene="leuC"
                     /locus_tag="BUpL06"
                     /EC_number="4.2.1.33"
                     /note="dehydratase component, catalyzes the isomerization
                     between 2-isopropylmalate and 3-isopropylmalate"
                     /codon_start=1
                     /transl_table=11
                     /product="isopropylmalate isomerase large subunit"
                     /protein_id="NP_057970.1"
                     /db_xref="GI:10957109"
                     /db_xref="GeneID:1109451"
                     /translation="MVNDMKKTLYDKIYDSHIVYEEKNNTSLLYIDLHLLHEVTSPQA
                     FDSLRDKNRKVRQPKKTFATMDHNVSTTSQDINASGSMAKVQMQELIKNCSEFNISLY
                     DIKNPNQGIVHVISPEKGMTLPGMTIVCGDSHTSTHGAFGALSFGIGTSEVEHVLATQ
                     TLKQQRFKNMKIEITGEIQKFVTAKDLILFIIGKLGSSGGAGYIIEFCGNVIEKMSME
                     ERMTICNMAIEIGAKSGLIAPDEVTFSYLKNKMYAPRGVFWKKALNFWKNLKSDKNAF
                     FDKVVNINISDLSPQITWGTNPDQVISIDQKIPDFSSFDNLIKKDLAKSACKYMGLKI
                     GTYLTNITVDKVFIGSCTNGRIEDLRAASKILKDKKIANNVKAIVVPGSGSVKREAEN
                     EGLDKIFISAGFEWRLPGCSMCLGMNKDRLNDGERCASTSNRNFEGRQGRGGRTHLVS
                     PIMAAAAAVYGKFVDVRKLYNGENN"
     gene            7163..7786
                     /gene="leuD"
                     /locus_tag="BUpL07"
                     /db_xref="GeneID:1109452"
     CDS             7163..7786
                     /gene="leuD"
                     /locus_tag="BUpL07"
                     /EC_number="4.2.1.33"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="NP_057971.1"
                     /db_xref="GI:10957110"
                     /db_xref="GeneID:1109452"
                     /translation="MFKFTGHAGIVVPLDISNIDTDIIIPKQFLKRVNKIGFGKYLFH
                     DWRFIDANQLVKNEDFILNKKIYKNASILLTRENFGCGSSREHAVWSLVDYGFKVIIA
                     PSFADIFYNNSFNNKLLLITLSSSEITFLFDIVKNNIGITFDVSLVEKTVTVNKEVFS
                     FELDDFHYFCLLNDLDNIDLTMKHLSEIKSYESRISDFLLERRDFKS"
ORIGIN      
        1 atgtaattat ttttttaaaa aaatagcgaa gtttttagaa ataaaaaact tcgctatttt
       61 tttttaattt aacaagtatg tttttattta tttttttata taagttttaa gaatgttatt
      121 ttgcatttat ttatataaga agcatttatt aaaaaaaaca gtatgcattt atttattttt
      181 tcaataaaaa aatgtgattc taatgttttt ttttattgaa aaaataaaat aagatgtttt
      241 atgataaaaa aaaagggggg gagataattt tacagtggat ttaagaaaca aaaaatatgc
      301 gaataaacgc atgcctttaa gaaagaataa atttaaataa aaattttaat tatcaggata
      361 agtgtttgta gctatcttgc gtaaataata atagcttata ttaacttgtt tctttaatcc
      421 attaggccct aatttagtta attcagtaat agagtatttg gctactaacg ctcgaagaat
      481 agtttgtctg gcttctttct catctaatga aatcaagcgt tgtgcatttc tctttttttt
      541 ataaaaagca tgcttagaaa ttctatattg aaaaatattt ttaatttgag tatctttaga
      601 acgtctttta gcatcaatca tggttattgg tttaaaacct ttactaatga gatttttatt
      661 gatccaccct aattgttgtt tcttagcatc cattaatttt ttttcagaaa caccaaagag
      721 cataaaaaac aatggggtta atgtgatcat tttgggcata taattgccta atattttatc
      781 ccatgttttt ttgcaagtaa caaaacccat aggttccata aaattagtaa ttaatctaga
      841 agcacgagta atagatttat tacctgcttt agacaaggta gacaaaccac attcatcaga
      901 taattgttca actgatgctt gaaccaaatc agaagaaata ttaaaatggt aaagcatagc
      961 taaaaccatg gctctcatag cacatgctcg gtgttcattt aatcttctaa atctttttac
     1021 gggaaaacca attttaatat ttttgatctg taaaatataa tttagttcgc atcgagctac
     1081 atctatttct gatgctcttt tcattgcata acaaataaaa gatggcctac gtttattatt
     1141 tttaggtggt gtaaaaaatg gattgggatt atttatatag cattttctta ttatcataac
     1201 atgatactta aaatagtaag tgggttcatt ttttatatat ttcaaatata taaaatttta
     1261 tttttattct ttcaataatt aaattttttt atatttaaga atatatactt tacttttatt
     1321 tttttttatg aataaatata atttataaaa aataaatata tttttaacat acattttgat
     1381 tattttcaac gataacttac taaaacttaa aagttttatc ttaactttct taaattaaat
     1441 aaaatatatt tataaattca atctatatca aaaacaatat tttttattaa caattactat
     1501 tcaggttaaa aaaatggaaa aaattattga aaaaagtata tatgcctctc gttggttaat
     1561 gtttcctgta tatgtaggtt tatcgtttgg ttttatttta ttaacattga aatttttcca
     1621 acaaattgta tttatcatgc cagatattgt ggctatgtca gaatcaggtt tagtgttagt
     1681 tgttttgtca ttaattgata ttgcattagt aggtggtcta ttagttatgg ttatgttttc
     1741 tggatatgaa aattttattt ctaaaatgga tatacaagat aatcagaaaa gattagggtg
     1801 gatgggaaca atggatgtta attcaataaa aaacaaagta gcatcttcaa tagttgctat
     1861 atcttctgtt catcttttac gtctttttat ggaagcagaa aaaatattag atgataaaat
     1921 tatgttatgt gttattattc atttaacttt tgtattatcg gcttttggaa tggcatatat
     1981 tgataaaatg agcaaaaaaa aacatatcct tcattagttt ttgtttaaaa aaaatttatt
     2041 tttttttaaa aaaactaata taaaagtata ttgttcaata tatgatttat caaaaactct
     2101 tcttttaaaa aaatatttta cttttaatta agtgtattta gtgcctagaa aaaattatat
     2161 atataatcta aaaccatttt ttaatccatc taaaaatgaa agaaaaaaat ctacatttat
     2221 ttgttatgca atgaaaaaag tatcagaaat agacgttgct agaagtcatt taaatcgtgc
     2281 attattacca atagatccta aaactggtaa tgttttgcct cgattcagac gattaaataa
     2341 acatcgagca tgtgctatga gagctatagt acctgctatg ttgtattatt ttaatattaa
     2401 ttctaaatta gtcgaagctt ctattgaaaa attagcagat gaatgtggat tatctacttt
     2461 atcagattct ggtaataaat ccatcactcg cgcttctcgt ttaataagtg agtttttgga
     2521 accaatgggt tttgttaaat gtaaaaaaat aaatagtaaa tcaatgagta attatatacc
     2581 taaaaaaatt tttttaactc ccatgttttt tatgttatgt ggtatttcac catcagaaat
     2641 aaatcatttt ttatcaaaaa aaataaaacc attaaaaaaa ttaaaaaaac aagaaaaaag
     2701 tgcatttatt tcttttacag atatgaagat tatatcgcaa ttagatgaaa gatcagctag
     2761 aacaaaaatt ttaaatgctt taattaatta ttacacggct agtgaattaa caaaaatagg
     2821 tccgaagggt ttaaaaaaaa agatagatat tgaatatagt aatttatgta atttatataa
     2881 aaaaaaatca taaaataaat ttatacaata aaaatttcat aagacatcat atacaaaatt
     2941 attttgtata tgatgtctta tgaaattttt attgtataaa tttattttta tccaataaaa
     3001 cattccatta ccttaatttg gaaaaatttt tatgaaatct aaagttgtta tttttgatac
     3061 cacgctacgc gatggagaac aagcattaca agcaagtctt agtgttaaag aaaagttaca
     3121 aattgcacta tctttagaaa aatgtgggat agacatttta gaaataggat ttcctgtttc
     3181 atcacccgga gattttaaat cagttcaaac tatatctaaa aatattaaaa atagtcgaat
     3241 atgtagttta gctcgttgta tagaaaaaga catcgatgca gccggagaag ctatgtcttc
     3301 atctgattct tttcgaattc atattttttt agctacttca acacttcata tggaatctaa
     3361 attaaagaaa aattttaacg aaataataga tatggctgtt ttttcagtaa aaaaagcttt
     3421 acgttatact gatgatattg aattttcttg tgaagatgct actagaacta caatggataa
     3481 tttatgtcgt attgtagaaa cattaattaa atcaggtgtg aaaacaatta atatccccga
     3541 tacagtagga tatactgtac ccaacgaatt atcttgtata ataaaaaatt tgtttgaaag
     3601 agtacctaac attcataaat ctataatttc agttcattgt catgacgatt taggcatggc
     3661 tgtgggaaat tcaatatcag ctatacaggc aggtgctaga caaatagaag ggactataaa
     3721 cggaattggc gaaagagctg gtaatacagc attagaagaa ataattatgg ctataaaagt
     3781 aagagaagat atcttaagtg tttccactaa tattaattat aaagaaattt atcgaactag
     3841 taaaattgtt agtcagattt gtaatatgcc aattccatct aataaagcta tagtaggtag
     3901 taatgcgttt gcacattctt caggtatcca ccaagatggt gtattaaaaa atagaaaaaa
     3961 ttatgaaatt atggaaccaa gtagtattgg tttaaaagaa gtaaaactta acttaacctc
     4021 tcgttctgga agagcagcag taaaacatta tatggatgaa atgggttata ataatagtga
     4081 ttataatata gatgaacttt atactgcttt tttaaagtta gcagataaaa aaggtcaggt
     4141 ttttgactat gatttagaag cattagcttt tattaataaa caacaagatg aatgggaata
     4201 cttttctttg aaatttttca gtgtgcagtc tatttctaat agtttatcta ctgcatcagt
     4261 aaaattatta tgtggcaaaa aaacatacac agaatcttct actacaagca atggaccagt
     4321 tgatgctatt taccaagcat taaatagaat tgcatgtttt cctattatat tacaaaaatt
     4381 tcaacttgta gctaagggga agggtaaaga tgcgttaggt caagtagata tcttagttga
     4441 acataaaaaa aggaagtttc atggagtggg tttggctact gatattattg aagcatcagc
     4501 tcaagcaatg atcaatgtac taaataacat atggaaagca aaacaagtta acaaaaaatt
     4561 aaaaatttta aaagatttta aaaaaaaata atacatctag atatagaaat ataatatttt
     4621 ttgttgattt ttattaaaga gaaaaatttt tatgaaaaaa aattatcgta tcgctgtatt
     4681 atctggtgat ggaataggtc ctgaagtcat gcaagaagca tgtaaaattt taaatgtttt
     4741 aaaaaaatat ttttttctat ctttagaaat acaaaaattt aatattggtg gtatagctat
     4801 tgaacgtgaa ggtgttgctt tgccaaaaac tacattgcta ggatgtgaaa attctgattc
     4861 aattttatta ggttctgtag gtggtaagaa gtgggataac cttccagtag aacaacgtcc
     4921 tgaaagagcc gctttattgc ctttaagaaa acactttaat cttttttcta atttaagacc
     4981 agcaaaatta tatccagaac taaaatgttt atcacctctt cgttcagata ttgtaaaaaa
     5041 tggttttgat atattatgtg taagagaatt aacaggtgga atttattttg gtgaacctaa
     5101 aggttttgta aataaaaaca atactaaata tgcttttgat acagaaattt atcatgagta
     5161 tgaaattatc cgtattgctc atttagcttt taaattggca cgatctagga agaagaaagt
     5221 ttgttctata gataaatcaa atgttcttca aagttctatt ttatggagag aagtagttga
     5281 aagtgtttct aaaaaatacc cagatgttca tttatctcat ttatatattg ataatgctgc
     5341 tatgcaaata attaaagatc ctaatcagtt tgatgtatta ttatgctcaa atctttttgg
     5401 agatattatt tctgatgaat gtgctacaat tacaggttca attgggatgt taccatcagc
     5461 aagttttaat gaaaaaaatt ttggattata tgagccggca ggcggatcag cacctgatat
     5521 tgaaggtaaa aatattgcta atccgattgc tcaaatactt tcactttcta tgttagttag
     5581 atatggcatg aatttaaatc agatagcaga taaaattgat aaagctgtta ataatgtatt
     5641 aaaaaaaggt tatagaactt cagatatatc tcatgataat aattttttaa aaacagatga
     5701 aatgggtgat cttattgttg attctttaat taatggtgaa tgacatgaag aaaacattat
     5761 acgataaaat atatgattca catattgttt atgaagagaa aaataataca tctcttttat
     5821 atatagattt acatttactt catgaggtta catcacctca agcctttgat tcattacgag
     5881 ataaaaatcg aaaggttaga cagcctaaaa aaacttttgc tacaatggat cataatgttt
     5941 cgacaactag tcaagatatt aatgcttcag gttctatggc aaaggtacaa atgcaagaat
     6001 taattaaaaa ttgttccgag tttaatatat cattatatga tataaaaaat cctaatcaag
     6061 ggattgttca tgttattagt cctgagaaag ggatgacttt gccgggtatg actattgtat
     6121 gtggtgactc acatacatcg acgcatggtg catttggagc attatctttt ggtattggta
     6181 cttcagaagt tgaacatgtt cttgcaactc aaacattaaa acaacagcgt tttaaaaata
     6241 tgaaaataga aattacagga gaaattcaaa aatttgtcac tgctaaagat ttgattttgt
     6301 ttattattgg aaaattagga tcatctggag gtgcaggata tataattgaa ttttgtggta
     6361 atgtaattga aaaaatgagc atggaagaaa gaatgacaat ttgtaatatg gcaattgaaa
     6421 taggtgcaaa gtcaggtttg atagcaccag atgaagtgac attttcttat ctgaaaaata
     6481 aaatgtatgc accacgtggt gttttttgga aaaaagcatt aaatttttgg aagaatttga
     6541 aatctgataa aaatgctttt tttgataaag ttgtgaatat aaatatttct gatctctcgc
     6601 cacaaattac ctgggggaca aatcctgatc aggtgatctc aatcgatcaa aaaatacctg
     6661 attttagtag ttttgataat ttaataaaga aagatttagc gaaatctgca tgtaaatata
     6721 tgggtttaaa aataggtact tatttaacta atattactgt tgataaagtt tttattggat
     6781 cttgtactaa tggaagaata gaagatttaa gagctgcctc aaagatactt aaagataaaa
     6841 aaattgctaa taatgttaaa gctattgttg ttcctggatc aggttcagtt aagagagaag
     6901 ctgaaaatga aggtttagat aaaatattta ttagtgcagg attcgaatgg cgtttacctg
     6961 gttgttctat gtgtttaggt atgaataaag atagattaaa tgatggtgaa cgttgtgcgt
     7021 ctactagcaa tcgaaatttt gagggtcgcc aggggagagg ggggcgaaca catttagtaa
     7081 gtcctattat ggcggctgca gctgctgtat acggtaaatt tgttgatgtt agaaaattat
     7141 ataatggtga gaataattaa atatgtttaa atttactgga catgctggta tcgttgttcc
     7201 tttagatata tctaatatag atacagatat tattattccg aagcaatttt tgaaaagagt
     7261 aaacaaaatt ggatttggta aatatttatt tcatgactgg cgttttattg atgcaaatca
     7321 attagtaaaa aatgaggatt ttatactcaa taaaaaaatt tataaaaacg caagtatttt
     7381 attaactaga gagaattttg gttgtggctc atcgagagaa catgctgttt ggtctctagt
     7441 agactatgga ttcaaagtaa taattgcacc tagttttgct gatatttttt ataataatag
     7501 ttttaacaat aagcttcttt taatcacttt aagttcgagt gaaattactt ttttatttga
     7561 tattgtaaaa aataatatag gtattacttt tgatgtaagt ttagtcgaaa aaacggttac
     7621 tgtaaataag gaagtatttt catttgaatt agatgatttt cattactttt gtttgttaaa
     7681 tgatttagat aatattgatt tgactatgaa gcatttatca gaaataaaat cttatgaaag
     7741 tcgtatatct gattttttat tagaaagaag agatttcaaa tcttaa
//
