LOCUS       NC_008507              14206 bp    DNA     circular BCT 31-OCT-2006
DEFINITION  Lactococcus lactis subsp. cremoris SK11 plasmid 5, complete
            sequence.
ACCESSION   NC_008507
VERSION     NC_008507.1  GI:116326645
KEYWORDS    .
SOURCE      Lactococcus lactis subsp. cremoris SK11
  ORGANISM  Lactococcus lactis subsp. cremoris SK11
            Bacteria; Firmicutes; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 14206)
  AUTHORS   Makarova,K., Slesarev,A., Wolf,Y., Sorokin,A., Mirkin,B.,
            Koonin,E., Pavolv,A., Pavlova,N., Karamychev,V., Polouchine,N.,
            Shakhova,V., Grigoriev,I., Lou,Y., Rohksar,D., Lucas,S., Huang,K.,
            Goldstein,D.M., Hawkins,T., Plengvidhya,V., Welker,D., Hughes,J.,
            Goh,Y., Benson,A., Baldwin,K., Lee,J.-H., Diaz-Muniz,I., Dosti,B.,
            Smeianov,V., Wechter,W., Barabote,R., Lorca,G., Altermann,E.,
            Barrangou,R., Ganesan,B., Xie,Y., Rawsthorne,H., Tamir,D.,
            Parker,C., Breidt,F., Broadbent,J., Hutkins,R., O'Sulllivan,D.,
            Steele,J., Unlu,G., Saier,M., Klaenhammer,T., Richardson,P.,
            Kozyavkin,S., Weimer,B. and Mills,D.
  TITLE     Comparative genomics of the lactic acid bacteria
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 103 (42), 15611-15616 (2006)
   PUBMED   17030793
REFERENCE   2  (bases 1 to 14206)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2006) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 14206)
  AUTHORS   Lucas,S., Copeland,A., Detter,J.C., Glavina del Rio,T., Pitluck,S.,
            Grigoriev,I., Rokhsar,D., Slesarev,A., Pavlov,A., Pavlova,N.,
            Karamychev,V., Polouchine,N., Shakhova,V., Kozyavkin,S.,
            Makarova,K., Koonin,E., Mills,D.A. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute (JGI), The Lactic Acid Bacteria
            Genome Consortium and Fidelity Systems Inc.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2006) US DOE Joint Genome Institute, 2800
            Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CP000430.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 2662180
            Source DNA and bacteria available from Bart Weimer
            (milkbugs@cc.usu.edu)
            Contacts: Bart Weimer (milkbugs@cc.usu.edu)
                      Larry McKay (lmckay@umn.edu)
                      Paul Richardson (microbes@cuba.jgi-psf.org)
            Annotation done by Kira Makarova and Eugene Koonin
            Finishing done by Fidelity Systems Inc. (Gaithersburg)
            URL -- http://www.fidelitysystems.com  Project Information
            available at: http://genome.jgi-psf.org/mic_home.html
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..14206
                     /organism="Lactococcus lactis subsp. cremoris SK11"
                     /mol_type="genomic DNA"
                     /strain="SK11"
                     /sub_species="cremoris"
                     /db_xref="taxon:272622"
                     /plasmid="5"
     gene            complement(939..2015)
                     /locus_tag="LACR_E1"
                     /note="LactoCOG number LaCOG03023"
                     /db_xref="GeneID:4405901"
     CDS             complement(939..2015)
                     /locus_tag="LACR_E1"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation ATPase FtsK/SpoIIIE related
                     protein"
                     /protein_id="YP_796565.1"
                     /db_xref="GI:116326646"
                     /db_xref="GeneID:4405901"
                     /translation="MTNSQLALYLLQSLNMALGSQIEGETSYTNSFDVKVQEDGFLFL
                     PRMPSGYIIDNDLYFKIFLIANACLYPRYTLLKQNSAYFIPINTDDIHTQRGLFFPWK
                     VGISKRLVINDLDFFVASQHKPYIPIMENLKLNYDNVTSIAIAGNSGSGKSYTLTYFL
                     SMLKPLSDLIIIDPKFDTPSRWARENKIPVIHPERNRSKSDFVAEINESLSQTLNIIY
                     KRQEILYDNPRHPFSHLTIVIDEVLALSEGTNKNIKDSFFSLISQIALLGRATKVHLL
                     LVSQRFDYQSIPVSVREQLNVLIQIGNINKKTVQFLFPDLDPEGIVIPLGKGTGLIQI
                     IDNEHPYQVLPLLCPTYYTKKGIL"
     gene            complement(2015..2335)
                     /locus_tag="LACR_E2"
                     /db_xref="GeneID:4405902"
     CDS             complement(2015..2335)
                     /locus_tag="LACR_E2"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_796566.1"
                     /db_xref="GI:116326647"
                     /db_xref="GeneID:4405902"
                     /translation="MKAQYNKRKGGYSAELANNILDRSKATHSLSETLEPQMKFEDGK
                     RTDEVIAYKGWFSQSGLPPFEVKFTDQVKLPPYLSIITFDHLQACEVNYNIYFKADGI
                     KEVK"
     gene            complement(2464..2961)
                     /locus_tag="LACR_E3"
                     /db_xref="GeneID:4405903"
     CDS             complement(2464..2961)
                     /locus_tag="LACR_E3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_796567.1"
                     /db_xref="GI:116326648"
                     /db_xref="GeneID:4405903"
                     /translation="MDFIKTGSKNRETYTYTFMSDGQKKTVTLVAGQDDITKEWIDEL
                     HRADDRTVYSNNKNANPDFRKKTKTHSEKKWNTSLDSPKPSAYDVKKGKFVEQSVVMP
                     ASYETPEQELLNDCLEKLSDDEASFLRRIVKRGEATKLAEEYHVSNKTINAWKNKLIN
                     KIKNF"
     gene            3297..4058
                     /locus_tag="LACR_E4"
                     /db_xref="GeneID:4405904"
     CDS             3297..4058
                     /locus_tag="LACR_E4"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_796568.1"
                     /db_xref="GI:116326649"
                     /db_xref="GeneID:4405904"
                     /translation="MTFNLEELFKQDVRGLNILEFSQYIEHTVADYKNFIKPKDREQF
                     LKSTIRITSSEIVKFLENTLGVELDREYNNHKRNQLNSLIKKIAPTQRGKRTVLDGYQ
                     FRDLILLDEFNKFVLNNFNSKNVKSEEKMYEEIMFLQQNKFKETQMYKAQKFEDNQTI
                     GYVLTLINGLAELLKEKYCLFLYLWKNNIFYGNIQASKEDKELLDIISYRFRQTNPLI
                     YKFDSEYDVNSTNNQQLIRFFVEDIDAWSKEITDR"
     gene            complement(4299..5210)
                     /locus_tag="LACR_E5"
                     /db_xref="GeneID:4405905"
     CDS             complement(4299..5210)
                     /locus_tag="LACR_E5"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_796569.1"
                     /db_xref="GI:116326650"
                     /db_xref="GeneID:4405905"
                     /translation="MEILKKRINNVEKYLSDISDNQKFFIGIKIELNKIQKILSEKFN
                     KTDENGLMFIPKPYNGIMAQRNTVGEFLSDKSKPKETAYRAQSWSLKDWGGNIHSGTS
                     EVPYKRYPKIFIDPLGLNFILLNDKQYLVINKQFNKKKSEYDKIKSAINLTLELFNKA
                     ETFILDVDTDMLKPVRQSVPWEILPQGVRIWNAFKDVANSNQVSKSDKILIEERFKYL
                     EEFKPDIEYQGTAGYSGYIAFAFSSKNIYVLDSILYGNATYIFGGNWEEISQLTKKQI
                     IDDNLYKYRIIHDKKWKTEIGNILNSI"
     gene            complement(5228..9910)
                     /locus_tag="LACR_E6"
                     /note="LactoCOG number LaCOG02239"
                     /db_xref="GeneID:4405906"
     CDS             complement(5228..9910)
                     /locus_tag="LACR_E6"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA or RNA helicase of superfamily II"
                     /protein_id="YP_796570.1"
                     /db_xref="GI:116326651"
                     /db_xref="GeneID:4405906"
                     /translation="MTKQTFDDLINQINTVSNDVQRERGTLFEKLTLAYLKNEPTYKA
                     LYQNVWLLSEVPESYGIPKKDTGVDLVAEQKNGDLVAIQAKFYTNKVGKSAINSFVAE
                     LGKSYYQRGLIVSTMDDWNSNARETIDQNEKGIEIIGLSDLRNSQIDWSQFNFERPEN
                     VVVKKPKKLREYQQTAKDNALSHFKENERGQLIMAPGTGKTFTSLKISEALAKDKNGP
                     FKVLYLVPSIQLLTQTLRGWNNDTELTITSMAVTYDRDASRGTDGTEDIKASDIGYPA
                     TTSSKKILQNWHDFESLPKPTDMLVVFSTYQSIEVIGEAQKEGFPEFDFIISDEAHRT
                     TGAHEATKEASAFSKVHSNTNVKGLKRMYQTATPKIYGESAKKNAKDKSILLSSMDDE
                     SKYGEVFFRMGFGQAVSRDILTDYKVMVLAVDEAAIQKDMQRTLADPENGLNIDDVGR
                     IVGIWNGMMRRNGYKNPIKNSPYDGAPLERAIAFTRTIEESKKVSGQFEEVVNEYISE
                     AIEDESIHLSMRHADGQMNALQKGEILDWLANPNKPADEARIVSNVRFLTEGIDIPTL
                     DAVIFLSPKKSQVDIVQAVGRIMRKAEGKDYGYIILPIVIPTGEKPETILDNNKNYET
                     VWQVINALRSVDERFEAMIDKLNMAKPKQLKVIGVGSAPDQVNDQDKTTENTPVQTEL
                     EFEWDKFEGAIFGKIVQKVGDRKYLENWSKDVAKIAERQINWIKNKLSDKKDPISLEF
                     KKFVSSLQHNINESIDENQAAEMLSQHLITKPIFEALFSEYSFVNQNPVSQAMESIVS
                     ELEKAGFAKEQENLEPLYESVRMRAEGIEKAEDKQKIIVTLYDKFFKTAFKSTTERLG
                     IVFTPIEVVDFIIHSVDDVLKKHFGKALASKDVHILDPFTGTGTFIVQTLNYLKEQMD
                     AGKTSLAEITRKFTQELHANEIVLLSYYIAAINIEATFDEINGEEKGYVPFEGIVLTD
                     TFESAETEDTLDDDYFGTNDARLKRQQEVPITAIIGNPPYSKGQSNDNDNNKNLEYPE
                     LFKSVANTYVKHSKTSSVLGMYDSYVLSIRWASNRLNGKGVVAFVSNGSYIDSQSADG
                     LRKSLYEEFNYLYIFNLRGDQRTSGETSRKEGGKIFGSGSRTPIAISILIKDDSDNHE
                     LYYHDIGDYLSREDKFEILSEAKSISGLDWLKITPDANNDWINQRDVNYSSYRAMAEE
                     DNSIFDLKDIGIVTNRDTWVSNFSDKKVSKNVATMIGNYNAEVDKLDSITDEINIKNV
                     NNYVTNDETKISWAASLRMAAVRKAKMSFNQDNIILSMYRPFTKKYLYRDRVINERVR
                     KSYITFPNSNSENYLINVAGTSNKSEFSVLMSDVVSDLMIITNSRNFPRYTYEESGIF
                     NNKIDNISNDDDFYYVYGVLHSPDYKHKYAPDLKKDLPRIPLLKNKEKYVEIGRKLAD
                     LHLNYEEQPNWDGVEVEISKPDYRVKKMKHPKKGVLNTIIYNESITIKNIPERAYDYV
                     VNGRPAIEWIIDQYQVKTDKKSGITDDPNDFSDDPKYILNLLLSVITVSMRTLELIDE
                     LPPFEVTE"
     gene            complement(9907..10581)
                     /locus_tag="LACR_E7"
                     /note="LactoCOG number LaCOG01517"
                     /db_xref="GeneID:4405907"
     CDS             complement(9907..10581)
                     /locus_tag="LACR_E7"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_796571.1"
                     /db_xref="GI:116326652"
                     /db_xref="GeneID:4405907"
                     /translation="MSENLKTIKELADELGVSKQTIRNKIDKDFREKFVQTIKIKGNN
                     TLVINNAGYSLLKKTLQNDTAQTAKTLQNDTAQTAKTLQNDTAQTAKTLQNDTAQTKL
                     ICFLEEQLDKKEQQLSVKDKQLENKDTQISQMQNLLDQQQRLALQDKKLLEEYKSEIN
                     ELKALKMPREDMKDGSSIRGEAQEEIERLKAKLKLSEEERNKAKEKEPVKTESKKWWH
                     FGRNVK"
     gene            complement(10574..11905)
                     /locus_tag="LACR_E8"
                     /db_xref="GeneID:4405900"
     CDS             complement(10574..11905)
                     /locus_tag="LACR_E8"
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiator protein"
                     /protein_id="YP_796572.1"
                     /db_xref="GI:116326653"
                     /db_xref="GeneID:4405900"
                     /translation="MEIITKNERNSNERTVCSLKEIEKRKIVEHNDLITSVAKMDKTP
                     LKIFELAVSCIDTENLPKDNTIYLSKEELFTFFDVSDNGKHTRFKEAIKVMQKEAFFE
                     IREEAGKGFKFKSIVPIPYVEWTDYHDEVKIEFHREIMPYLIELKKNFTQYALSDVME
                     LNSKYSIILYKWLSMNYNQYEHYSAKGGRRVNQVESYRNPSITVKELREITDTIHEYK
                     DMSNFTKRVLDNSLKEINHHTSFNVTYDKIKKGRSIDSIVFHIEKKPVAKNEYYKQEE
                     QDPVYLENKADREAKQKMLFAEAMQSPYTKLLGEKWLINVADMQDISTMTGLAEKVYP
                     LYDELKEARGLKGVETHLSYVASKQEGYSKRNVVKYLKTAIEGYLPTVALQDLEQPER
                     ANYKKPRSLEEVAKDFLPDYQNETSEAEKEELRRLKAEIDKKLRGEGLDHE"
ORIGIN      
        1 accgattctt gatagatgag aaatgcccat ttgttgctac gctgttcttt tttcttttgt
       61 ttcataatag atataacctt tctatttatc aggagaattg atttattttt tcggagcttt
      121 ttaatatatt tttttgatta ttgattattg agctaatggg ggtcgtagta accccattac
      181 acgatgattg tattactcat atagatttga gtgattggta aattaccttt ctaaatataa
      241 cggcgacaaa aagggatgaa ttttacccca gattaaaata tttgtataaa aaatggcgct
      301 tgtggctctt actttgtaag ccacagcgcc agattaatta tttacgtttt gtgccttgta
      361 accataattg gttacgatga cgttcaaaat tagagaagat atactcagga ttttggtttg
      421 aaatttcttc tttaatttga gcttcaagct ctttcagaat cttttgagtc tgttgggtgc
      481 tcggaatttt gataaagact aaaatttcgc cattttttac gtcaatgcag gacttacgga
      541 cagcgcgatt aaatttctcg ttgatgggat taaaaatggt cactttttga gtttctacaa
      601 tttttccgga gcgttcgctt tgtctcatga atcgtcggag attaaaagtt tgcttgattg
      661 acttgaaata attgatccag gaatcggatt tgaaacgctt gatgagttca agagttgtga
      721 ggagggtgac aagagaaagc aaccctacac tgagttcaaa agtgaagtta gaaaacgctg
      781 aaatagagtt actgagctta aaaagtggta gtaaacttga tttttcaaaa cttgcactca
      841 tgaaatcaag aaaaactgtg ataataaaag ttgagattga aaacaaaacc aatctcaaat
      901 tgagattgaa tgtcctcatg aaataagtct ttttcatgtt agagaatacc tttcttcgta
      961 tagtaagttg ggcataacaa gggaagcact tgataaggat gctcgttgtc aatgatctgg
     1021 attaaaccag tacctttacc taatggaata acaattcctt caggatctaa atcaggaaac
     1081 aagaattgaa cagttttctt attgatattt ccgatttgaa taaggacatt taactgctcc
     1141 ctcacagaaa ctggaataga ttgataatca aaacgttgtg ataccagtaa aagatggact
     1201 ttagtcgctc ttcctaacaa tgcaatctgt gaaattaaag agaagaagct atccttaata
     1261 tttttgtttg ttccctcgga tagagccaag acttcatcaa taacaatagt cagatgtgaa
     1321 aacggatggc gaggattatc gtatagaatc tcttgacgct tataaatgat attcaaagtt
     1381 tgacttaaag attcgttgat ttcagcaaca aaatctgatt ttgaacgatt gcgttcaggg
     1441 tggattacag gaattttatt ttctctcgcc cagcgtgacg gcgtatcaaa tttaggatca
     1501 atgatgatta aatctgatag aggctttaac atacttagaa aataagtaag tgtataagat
     1561 ttaccacttc ctgaatttcc tgcgattgca attgaggtta cattatcgta gtttagtttc
     1621 aggttctcca tgatagggat atagggctta tgttgtgaag caacaaagaa atctaaatcg
     1681 ttgataacta aacgctttga aataccaacc ttccaaggga agaacaagcc tcgttgcgtg
     1741 tgaatatcgt cagtatttat tggaataaaa taggcgctat tttgcttaag taaggtgtat
     1801 cggggataga gacaagcgtt cgcaatcaag aaaatcttaa aatacaggtc attgtcaata
     1861 atatagcccg aaggcattcg aggaagaaag aggaagccat cttcctgtac tttgacatca
     1921 aaactatttg tatacgaggt ttcgccctca atttgagatc ctagtgccat attcagactt
     1981 tgtaagagat aaagtgcaag ttgactattg gtcattattt tacctccttg atgccatcgg
     2041 ccttgaagta aatgttatag ttgacttcgc aggcttggag atgatcaaat gtgataatag
     2101 atagataagg gggaagttta acttgatctg tgaattttac ttcaaagggg ggtaaaccgc
     2161 tttgagaaaa ccaacctttg taagcaatca cctcatcagt tcgtttgccg tcttcaaact
     2221 tcatttgagg ctcaagcgtt tcgctcaatg agtgagtggc ttttgagcga tctaaaatgt
     2281 tgtttgcgag ttcagcggag tacccgcctt tgcgtttatt atattgtgct ttcatagtga
     2341 ttcctttcat gaatcggtag tttaatgtgt gctgctcagt ttttatcgtg agcttgattt
     2401 ttcctccttc tataaataac ggcgacaaaa aaagagggat tttaccctct tttgaaattt
     2461 ttattaaaaa tttttaattt tattgatgag cttgtttttc caagcattga tcgtcttatt
     2521 agaaacgtgg tattcttctg cgagtttggt agcttcgccc cgttttacaa tgcgtcttaa
     2581 gaagctcgct tcatcatctg aaagtttttc aaggcaatca ttcaaaagtt cttgctcagg
     2641 ggtttcatag gaagcaggca ttacaacgga ctgttctaca aactttcctt ttttgacatc
     2701 ataagctgaa ggtttgggag agtctaatga agtattccac tttttctcag aatgtgtctt
     2761 tgtttttttt ctgaaatcag gattcgcatt tttgttgttt gaataaactg tacgatcatc
     2821 agcacgatga agctcgtcaa tccattcttt agtaatgtca tcttgcccag cgactaaagt
     2881 taccgtcttc ttttgaccat cactcataaa tgtgtaagtg taagtttcac gattcttaga
     2941 acctgttttg ataaaatcca ttttgtgctc ttttccgccc ttaggacgga taggaaacag
     3001 gatttattga ttaaccgaat tggcaaaagg cacaccaaat aaacggaaga ccaacaaacg
     3061 gtaagccaag acaaatgagt caggctttcc tttgttttca atccgtccat ttaggtgcgc
     3121 accagtatag gactgtttat atttacaaga attatcttgc ataatataat tatcccaata
     3181 ataggggtaa aatactaact tatcaacaag atataatttt aatagaatat tgattataaa
     3241 ggagatttac gataaaatga taagaaaagt aacttttttg aggtggggaa atggaattga
     3301 cttttaattt agaagaatta ttcaaacagg atgttagagg attaaatata ctagagttct
     3361 cacaatatat agagcataca gttgcagatt ataagaattt tattaaacct aaagacaggg
     3421 aacaattttt gaaatcaact attcgtatta catcaagtga gatcgttaaa tttcttgaaa
     3481 atacactagg tgtagaatta gatagagaat ataacaatca caaaaggaat cagttgaatt
     3541 ctctaataaa aaaaatagcc ccaacccaaa gggggaagag gactgtatta gatgggtatc
     3601 agtttagaga tttgatttta ttagatgaat ttaataaatt tgtgttaaat aattttaatt
     3661 caaaaaatgt gaaaagtgaa gaaaaaatgt atgaagaaat tatgttctta caacagaata
     3721 aattcaagga aacccagatg tataaggcgc agaaatttga agataatcag acaataggtt
     3781 atgttctaac tttaataaat ggacttgcag agttgttgaa ggaaaaatat tgcttatttt
     3841 tgtatctatg gaaaaataat attttttatg gaaatattca agctagtaaa gaggataaag
     3901 agctactaga cattatttct tacaggttta gacaaacgaa cccattaata tataaatttg
     3961 attcggaata tgatgtaaat tctactaata atcagcaact cattagattt tttgtagaag
     4021 atatagatgc atggtctaaa gaaataactg atagatgaga cgattaaatt ttgagaaggt
     4081 acacaaagtg gaatggcaag aaaaaatgaa tatattacaa tgatacttaa atacttaatg
     4141 ggtttaaaaa cattattcat ttgcttactc cttttagagt tattatatca ttataaaaaa
     4201 aaatagcccc taagatctaa atgttagatc ttaggggcta ttttaacggg atttttcagg
     4261 ggttattatc taataataac ccctatgaaa acagatttct agatagaatt aagaatattt
     4321 cctatttcag ttttccattt tttatcatgt ataattctat atttatataa attatcatca
     4381 attatttgtt ttttagttaa ttgagatatt tcctcccaat taccaccaaa aatatacgta
     4441 gcatttccat acaagataga atctagaaca tagatatttt tacttgaaaa agcaaaagct
     4501 atatatcctg aatatccagc agtaccttga tactcaatat ctggcttgaa ttcttctaaa
     4561 tatttaaatc tttcttcgat taatatttta tcactttttg atacttgatt agaattagct
     4621 acatctttaa aagcattcca aattctaacc ccttggggaa gaatttccca aggaacactt
     4681 tgtctaactg gttttagcat atctgtgtct acgtctagta taaaagtttc agctttattg
     4741 aataattcta acgtgagatt gatggctgat tttattttgt catattcaga ttttttttta
     4801 ttgaattgct tattaattac taaatactgt ttatcattaa gtaaaatgaa gttgagtcct
     4861 aaggggtcta taaaaatttt tggatatctt ttataaggta cttcactagt tccagaatga
     4921 atatttcctc cccaatcttt tagagaccaa ctctgagcgc gataggcagt ttctttgggt
     4981 ttacttttgt cagataaaaa ctctcccacg gtattacgtt gagccattat tccattatag
     5041 ggttttggaa taaacatcaa tccattttcg tcagttttgt tgaatttttc tgatagtatt
     5101 ttttggattt tgttcagttc aattttaatt ccgataaaaa atttttggtt gtctgaaatg
     5161 tctgatagat atttttcaac attattaatt ctttttttta atatttccat tactaaggcc
     5221 ttctttctta ttcggttact tcaaatggtg gcaattcatc aattaattca agtgtacgca
     5281 tacttactgt aataacagat agtaggaggt tcaaaatata cttaggatca tcactaaaat
     5341 cattaggatc atctgtaata ccagattttt tatctgtttt aacttgatat tgatcaataa
     5401 tccattcaat cgcaggccga ccattaacaa cataatcata tgccctctct ggaatattct
     5461 taatagtaat actttcatta taaataatcg tatttaatac acctttttta ggatgtttca
     5521 tcttcttaac acgataatca ggtttcgaaa tttcaacttc aacaccatcc cagttgggtt
     5581 gttcttcata atttagatgt aaatcagcaa gcttacggcc aatttctacg tatttttctt
     5641 tgtttttcaa taaagggata cggggtaaat cttttttaag atcaggtgca tatttatgtt
     5701 tatagtcggg cgaatgaagt acaccgtata cataatagaa atcatcatcg tttgaaatat
     5761 tatctatttt attgttaaaa ataccggatt cctcataagt atatcgcggg aaatttcgtg
     5821 aattcgttat aatcattaaa tcggaaacga catcactcat taatactgaa aattcagatt
     5881 tatttgaagt accagccacg ttaattaagt agttttctga gttgctattt gggaaagtga
     5941 tataagattt acgaacacgt tcattaataa ctctatctct atacaaatat tttttagtga
     6001 aaggtctata catagataaa ataatattat cttgattaaa tgacattttt gctttacgaa
     6061 cagcagccat tcttaggctc gctgcccagc tgattttagt ttcatcattt gtcacataat
     6121 tatttacatt tttaatattt atttcatcag ttatagagtc taacttatca acttcagcat
     6181 tataattccc tatcatagta gcaacatttt tgcttacttt tttgtcagaa aaattactta
     6241 cccaagtatc tcgattggtg acaataccaa tatcttttaa atcgaaaata gaattatctt
     6301 cttctgccat agctctataa cttgaataat ttacatctcg ttgattaatc caatcgttat
     6361 tagcatcagg tgtaatcttt aaccaatcta atcctgaaat agattttgcc tcacttaaaa
     6421 tttcaaattt atcttcacga cttaaataat ctccaatatc gtggtaataa agttcatgat
     6481 tatcactatc atctttaata aggatagaaa tcgcaatagg tgtacgactt cctgaaccaa
     6541 atatttttcc accttccttg cgggaggttt cgccagatgt tcgttggtca ccccttaaat
     6601 taaaaatata taaatagttg aattcttcgt aaagtgattt tcttaatcca tctgctgatt
     6661 gactatctat gtatgatcca ttagaaacaa aagccacaac acccttacca tttaaacggt
     6721 ttgaggccca acgaattgat aaaacataac tatcatacat tcccagtaca ctacttgttt
     6781 tagaatgttt tacgtatgta tttgcaacag acttgaataa ttctgggtat tctagatttt
     6841 tattattgtc gttgtcatta gactgtcctt tcgaataggg aggattaccg ataatagcag
     6901 taattggaac ttcttgttgt cgtttcaacc gtgcatcatt agttccaaag taatcatcat
     6961 ctaatgtatc ttcagtctct gcactctcaa aagtatccgt taagacaatc ccttcaaaag
     7021 gaacatagcc tttttcctca ccgtttattt catcaaaagt tgcttcaatg ttaatggccg
     7081 caatgtaata gcttaacaaa acaatttcat tcgcatgtaa ttcttgagta aatttacggg
     7141 taatttctgc caaagaggtt tttccagcat ccatttgttc ttttagataa ttcaacgttt
     7201 gaacaataaa cgttcccgtt cctgtaaatg gatctaaaat atggacatcc ttgctcgcta
     7261 aagcttttcc aaagtgcttt ttaagcacat catcaacaga atgaataatg aaatcgacaa
     7321 cttcaattgg agtaaagaca atccctaatc tttcagtcgt tgatttaaaa gcagttttga
     7381 agaatttatc atataaagta acaataatct tttgtttgtc ttctgctttt tcaatacctt
     7441 cagcacgcat tctgacagac tcgtataaag gttctaggtt ttcttgttct ttggcaaagc
     7501 cagctttttc tagctctgat acaatcgatt ccatcgcttg cgagacggga ttttgattta
     7561 caaaactata ttccgaaaat agtgcctcaa atataggctt tgtaattaaa tgctgtgaga
     7621 gcatttccgc agcttgattt tcatcaatac tttcattgat attatgttgt aatgatgaaa
     7681 cgaacttttt aaattctaaa ctaatcggat cttttttgtc tgataactta tttttaatcc
     7741 agttaatttg acgctcggca attttagcaa catctttcga ccaattctca agatatttac
     7801 gatctccaac tttttgaaca attttaccaa aaatagctcc ttcaaattta tcccactcaa
     7861 attcaagttc agtttggaca ggagtatttt cagtagtttt atcttgatca ttcacttgat
     7921 ctggagcact tcctacacca ataactttta actgtttagg ttttgccatg tttaacttat
     7981 caatcattgc ttcaaatcgc tcatcgacag agcgtaaagc attaatcact tgccaaactg
     8041 tttcgtaatt cttgttattg tctaatattg tttctggctt ttctccagtt ggaataacaa
     8101 ttggtaagat aatatatcca tagtctttac cttcagcctt acgcatgata cgaccaacag
     8161 cttgaacaat atcaacttga gatttcttag gagataaaaa tataactgca tcaagtgtcg
     8221 gaatatcgat accctctgtt aagaagcgga cattagaaac aatccgtgct tcatcagctg
     8281 gtttattagg atttgctaac caatctaaaa tctctccttt ttggagtgca ttcatttgtc
     8341 catccgcatg acgcattgat aaatggatag attcgtcttc aatagcttcg ctgatatatt
     8401 cattgactac ttcttcgaat tgacccgata cttttttcga ttcttcaatt gttcgtgtaa
     8461 aggcaatcgc tcgttctaaa ggggctccat cataaggact atttttgata ggattcttat
     8521 agccattacg gcgcatcatt ccgttccaaa tccccacaat acgaccaaca tcatcaatat
     8581 tcaagccatt ttctggatca gcaagcgttc gttgcatatc tttttgaatt gctgcttcat
     8641 caactgctaa aaccatcact ttataatcgg ttaggatatc acgtgaaact gcttgaccaa
     8701 atcccatacg gaagaacact tctccatatt tactttcatc atccattgat gagagtaaaa
     8761 tactcttgtc tttagcattt tttttagcac tttcaccata tatctttggt gtagctgttt
     8821 gatacattct tttcagccct tttacattgg tattgctgtg aactttagag aatgcactgg
     8881 cttctttagt tgcttcatga gcacctgtcg ttctatgagc ctcatcagag ataataaaat
     8941 caaactcagg aaacccttct ttttgggctt caccaatgac ttcaatactc tgatacgtac
     9001 taaaaacaac gagcatatcg gttggttttg gcaatgattc aaaatcatgc cagttttgca
     9061 atatcttttt actagaagtg gttgctggat aaccaatatc agaggctttt atatcctcag
     9121 ttccatctgt accacgtgac gcatcacggt catatgtaac agccatactc gttattgtaa
     9181 gttcagtatc attattccaa ccacgcaatg tttgggtcag caattggata ctcggaacaa
     9241 gatataacac tttaaaagga ccatttttat ctttagctag agcttcagaa attttaagac
     9301 tagtgaatgt ttttcctgta cctggcgcca taatgagttg accacgttca ttttctttaa
     9361 aatgagaaag tgcattatct ttggctgttt gttggtactc tcttaatttt ttaggttttt
     9421 taacgactac attttctgga cgttcaaaat taaattgaga ccagtcaatt tgagagtttc
     9481 taaggtctga taatccaatg atttcaatcc ctttttcgtt ctgatcaatc gtctcacgtg
     9541 cattggaatt ccaatcatcc atcgtagata caataagccc tcgttgataa taacttttcc
     9601 ctaactcagc aacaaaggaa ttaattgcag acttaccaac cttatttgta taaaatttgg
     9661 cttgtatcgc aaccaaatca ccattttttt gttcagcaac taagtcaaca cctgtatctt
     9721 ttttgggaat accataagat tcaggaactt ctgacaataa ccatacattt tgatacaagg
     9781 ctttgtaagt tggttcattt tttaaataag ccaacgttag tttctcaaaa agcgtcccac
     9841 gttctctttg tacatcgtta gaaacagtat taatctgatt aattaaatca tcaaaagttt
     9901 gtttagtcat tttacattcc ttccaaaatg ccaccatttt ttagattctg tttttacagg
     9961 ctctttttct tttgccttgt ttcgttcttc ttctgataac ttcaatttag ctttcagtcg
    10021 ttcaatttct tcctgcgcct caccccttat cgacgagcca tctttcatat cctcccgagg
    10081 cattttaaga gctttcaatt cattgatttc tgatttatac tcttctagta attttttatc
    10141 ctgtaaggct agacgttgtt gttggtctaa aagattttgc atttgtgaga tttgagtgtc
    10201 tttattttct agttgcttat ctttaacaga taattgctgt tcctttttat ctaattgttc
    10261 ttctaaaaaa catattaatt tagtctgtgc agtatcattt tgcagtgttt ttgcagtctg
    10321 tgcagtatcg ttttgcagtg tttttgcagt ttgtgcagta tcattttgca gtgtttttgc
    10381 agtctgtgca gtatcatttt gcagtgtttt ttttagtaaa gagtaccctg cgttattaat
    10441 tactaaggta ttattacctt taatttttat tgtttgaaca aacttttctc taaaatcttt
    10501 atctatttta tttcttatcg tctgttttga tacgcctaac tcgtccgcaa gctccttaat
    10561 agtttttaaa ttctcactca tggtctaagc cctcgccacg taacttttta tcaatttctg
    10621 ctttcaatcg tctcaattct tctttttccg cttcgctagt ttcgttctga tagtctggta
    10681 aaaagtcctt tgccacttct tctaaacttc ttggcttttt atagttggct cgttcaggtt
    10741 gttcgaggtc ttgtaaagca acggttggta aataaccctc aatggctgtt ttaaggtact
    10801 taaccacgtt tcgtttagaa tagccctctt gcttacttgc aacgtatgat agatgtgttt
    10861 ctaccccttt taatcccctt gcttctttga gttcatcgta tagtgggtaa actttttctg
    10921 caagtcctgt catggtactt atatcttgca tatcagcaac attaattagc catttttcgc
    10981 ctaataactt ggtgtaagga ctttgcatag cttctgcgaa aagcattttt tgtttagctt
    11041 ctcggtctgc tttgttttca agataaactg ggtcttgttc ttcttgctta taatattcat
    11101 ttttagcaac tggttttttc tcaatatgaa agacaataga gtcaatgctc cgcccttttt
    11161 taattttgtc ataggtcacg ttaaaagatg tatggtggtt aatttccttt agtgaattgt
    11221 ctaaaactct tttcgtaaaa ttgctcatat ctttatactc atgaatcgta tcagttattt
    11281 ctcgtaattc tttgacggtg attgagggat tgcggtaact ttctacttgg ttgactcgcc
    11341 gtccgccttt ggcactgtaa tgctcgtact ggttataatt catggataac catttataaa
    11401 gaataatgct gtatttactg tttaattcca taacatcaga taaagcatac tgcgtaaagt
    11461 tcttctttaa ctcaatcaga tagggcataa tttcacgatg aaattcaatt tttacttcat
    11521 catgataatc tgtccattct acgtaaggga taggaacaat gcttttaaat ttaaaaccct
    11581 tgcctgcttc ttctctgatt tcaaaaaaag cttctttttg cataaccttt attgcttctt
    11641 taaaacgggt atgtttccca ttatccgata catcaaaaaa agtaaacaat tcttctttag
    11701 ataagtaaat ggtgttgtct ttaggtagat tttccgtatc aatacaagac acagccaatt
    11761 caaaaatctt taaaggtgtt ttatccattt tggcaacgga cgttatcaag tcgttgtgtt
    11821 caacaatttt tcgtttctcg atttctttca aagaacacac tgtcctttca ttgctgtttc
    11881 gttcgttttt tgttataatt tccatgataa gttgctcctt atgagtaatt ttagttaagc
    11941 atagagaagt catttagcgg tgtactttct ctatgctttt attatatcac tttaatcagt
    12001 acacgtaaaa ttattttgta ctgatataca ttgttttttg tactgatata cattgttttt
    12061 tgtactgata tacattgttt tttgtactga tataattctg tgacacctta taaacactga
    12121 cttttttttc acgcaaaaga acaaaagatt aaaatatata agataaatta atataggctt
    12181 cgcctttttt cactccgttt aaaaatctta aaatcaaggt caaaagaaaa agtcaaaacc
    12241 acttttagaa atttattgga ttccctctaa ttgctcatat aagctgtttt agctgtttga
    12301 ctagctaaat actcatatca tgcaatcaag cgtcttacag acggtcaggt cagggcaagc
    12361 cctaacaacc cttaaatgga aaaccgatac tttgtttaac ttgttttttt acaacttaca
    12421 acaagctatt caattcaaaa tcaatttaaa cccacttaaa agctcgttta agcattctta
    12481 atgctccctt tgaacaaata gacagtatcg aattaaagtc gcttaaatcg agttttagaa
    12541 cgttttaaaa tagaatgatt aaaactaaaa agtttcaaac gctggtcggc ttgtttcgtt
    12601 aaaaaagagt gcaatgcgca cttacacatc cctctaaaaa cgagtgatgt aatggctaaa
    12661 aatcgtgtat cagaagttgc ttatcgcaac aacaaaactt catgatagta gcgtctctta
    12721 aatgagtgag tctttgttta aatttgtgat acatttttct gatccatcaa gaacttcctc
    12781 aaagataaaa tgcctcagcg ctcattcctc aatcgccctt tgtcattgat tttgtaataa
    12841 gcattgcgcc ctattcggtt gcaatcctca caacaaaata gaccatataa aaccataaat
    12901 actgcaagct atcacattgt aatacaaagc acttcgttct tgtattacaa tgtggcttga
    12961 aaagggggaa gtttcacttt ccccttttat cccctttgga ttgtgtcgat ttgctttacg
    13021 cgaacgccac ctacccattt tataaaaata aaatgggcaa aagatctttc tttttgtcat
    13081 acaaaaagaa gaaaaaaaga gacgattttc ttcttccgaa atcgtccctc ttttttctaa
    13141 aaccatggat gaacaaacaa aatacgagag attttttgtt cgttcatcca ctaaaaagaa
    13201 ctccctaacg gtcgtggcta ctttgtttag tctaaacgct ttgaatagtc ctataagctc
    13261 atagtttgcc ttctaagcga ttttaaacgt gagttagtaa taataaaaag cccttaaata
    13321 ggcttgtatg taattgacta aaacgtacaa ttttagcttt taaatatgac ccttacttat
    13381 gacctgctct aacctcacta ttcatcagca ttcaaaaaac agctcacaac tgttaagtta
    13441 tgatctactt ttggttccgt tgcaaatttt aaaaatcgat ctaaatatcg tataattaac
    13501 ccgaattgct agttgattat ttagccatga cttgataccc gatagaatat cttaaagtct
    13561 ctggttccag tgatttagct gattttaaca ataaagaata cgctaaaagt atcatctcta
    13621 attccaataa acttggaagc ttgttcacga tttagtagat atggatagtt attttccatg
    13681 gttatcctcg tcatcttttt gttttatttc gatgtagcgt ttagagtcca aatatatttt
    13741 gaagaagtaa ctcttgctga atacaaaata caacaagtca ggaaattgtt ttgcgattaa
    13801 atcggtaaaa tcagcaaatt cttttatacc agaatcacgc atcacttcat agacctggtt
    13861 aagtaaatct tcattattct cagctaagaa tttatcaagc tcaaaacccg ctcctgattc
    13921 aatgtcttcg atgttataag gagacttttc tggattctca gcgtgtgtga aataatcgta
    13981 cattcccttt ggactcatta ccacttcgac atgttcgggg gaattcagct tatcactgat
    14041 gagttctgaa acttgtgaat agcttttaag tgattcgaag aaaaatacac catgtttgtg
    14101 tggctttttg aactcgccgg tcgtgcggtt tacatcttta tcatgccaag gggataagat
    14161 aaatggtaca tggagctctt ctaagagatt caagtaatct tcgggt
//
