LOCUS       NC_009660              12917 bp    DNA     circular BCT 04-DEC-2007
DEFINITION  Kineococcus radiotolerans SRS30216 plasmid pKRAD02, complete
            sequence.
ACCESSION   NC_009660
VERSION     NC_009660.1  GI:152963954
KEYWORDS    .
SOURCE      Kineococcus radiotolerans SRS30216
  ORGANISM  Kineococcus radiotolerans SRS30216
            Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
            Frankineae; Kineosporiaceae; Kineococcus.
REFERENCE   1  (bases 1 to 12917)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Glavina del Rio,T.,
            Hammon,N., Israni,S., Dalin,E., Tice,H., Pitluck,S., Saunders,E.,
            Brettin,T., Bruce,D., Detter,J.C., Han,C., Schmutz,J., Larimer,F.,
            Land,M., Hauser,L., Kyrpides,N., Lykidis,A., Bagwell,C.E.,
            Shimkets,L., Berry,C.J., Fliermans,C. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of plasmid pKRAD02 of Kineococcus radiotolerans
            SRS30216
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12917)
  AUTHORS   Copeland,A., Lucas,S., Lapidus,A., Barry,K., Glavina del Rio,T.,
            Hammon,N., Israni,S., Dalin,E., Tice,H., Pitluck,S., Saunders,E.,
            Brettin,T., Bruce,D., Detter,J.C., Han,C., Schmutz,J., Larimer,F.,
            Land,M., Hauser,L., Kyrpides,N., Lykidis,A., Bagwell,C.E.,
            Shimkets,L., Berry,C.J., Fliermans,C. and Richardson,P.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JUL-2007) US DOE Joint Genome Institute, 2800
            Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
REFERENCE   3  (bases 1 to 12917)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-APR-2003) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CP000752.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 3436090
            Source DNA and bacteria available from Christopher E. Bagwell
            (christopher.bagwell@srnl.doe.gov)
            Contacts: Christopher E. Bagwell (christopher.bagwell@srnl.doe.gov)
                      Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Additional Notes: Kineococcus radiotolerans SRS30216 has 3
            replicons, a chromosome and two plasmids.  The chromosome and the
            largest plasmid, plasmid 1, both appear to be linear.  We have
            performed various pcr reactions in an attempt to circularize them.
            None have succeeded.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..12917
                     /organism="Kineococcus radiotolerans SRS30216"
                     /mol_type="genomic DNA"
                     /strain="SRS30216"
                     /db_xref="taxon:266940"
                     /plasmid="pKRAD02"
                     /note="type strain of Kineococcus radiotolerans"
     gene            complement(443..901)
                     /locus_tag="Krad_4699"
                     /db_xref="GeneID:5333479"
     CDS             complement(443..901)
                     /locus_tag="Krad_4699"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355388.1"
                     /db_xref="GI:152963955"
                     /db_xref="GeneID:5333479"
                     /translation="MPQELPPDHPYLVAMKVNAMRQALGQSPLPMPPAPAVMRSASGR
                     EDGPGAERAAAVRAHAEAMVAALPPGNRAVVDPTTMAATEAAIRSAAAAVTEAVTPDP
                     ASQAAQALQQRVQDAIAAQLRELATPPQGPPAKPWEPEPRPRGDHTGIVL"
     gene            complement(901..1308)
                     /locus_tag="Krad_4700"
                     /db_xref="GeneID:5333480"
     CDS             complement(901..1308)
                     /locus_tag="Krad_4700"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355389.1"
                     /db_xref="GI:152963956"
                     /db_xref="GeneID:5333480"
                     /translation="MLPRDARSHRRPAGWTDLPVLGTAPNWSRPQQVPEVVREAGKDA
                     VAEFWLLWSSPMASQWDPAADLAVTVRVVLLRTAIARGDEAGAKRMAELRALEDRLGL
                     SALARERLRWHLPTAAPTEDDASVISLSSYLEN"
     gene            complement(1518..1787)
                     /locus_tag="Krad_4701"
                     /db_xref="GeneID:5333469"
     CDS             complement(1518..1787)
                     /locus_tag="Krad_4701"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355390.1"
                     /db_xref="GI:152963957"
                     /db_xref="GeneID:5333469"
                     /translation="MNLYRRRQQVPEPGLLQAVVAIDPTCCRCGSGPCVAVIAHPVPA
                     PTLRALGIDPRDPDRCRGVCSRCAAAARARRPRRFAISAGAGGRA"
     gene            complement(1784..4459)
                     /locus_tag="Krad_4702"
                     /db_xref="GeneID:5333484"
     CDS             complement(1784..4459)
                     /locus_tag="Krad_4702"
                     /note="KEGG: mkm:Mkms_3589 conserved hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355391.1"
                     /db_xref="InterPro:IPR001553"
                     /db_xref="GI:152963958"
                     /db_xref="GeneID:5333484"
                     /translation="MSAVEPVSYLPQHDGAQFLQHVQSLVPPGFLVSLTGAFPDRAVP
                     WTVHLDTAEQAEAIASSWSSAASSVWLRVCSQRQRPERGRGGDTASAVLPGAWFDGDT
                     LLAHETPEREDGLVLPRDSEQLAQLFSQVLPPPSLLVDSGHGQHPYLLLEHPELIDDG
                     NRAAVAALLRRLGEGVARGFAAQGFVYDPKPHDLARVLGAAGTVSRKPGRRPVLRRIL
                     LADGPRYTLAHLQQWSADLDARHPVSVSRTPPSAFSVGAPARSAPTTNTGRFLADETG
                     GGTNLLETLAAHLSVREVLEAAGWTAVAQSPTGELQWRRPGNPSNPVSGHSGHDGHDV
                     FVNWSDNADLPTGVGLNVPRLLSHLAGFGGDLSAFCHKLQPALNGVPGAATFGIPAHV
                     VAVLQERHVQRRGSRASSPLPAAALPLALLQHRHDVTADAERGRENAGLDSGEDTGPH
                     AGEDGGEPVRATWAPVDLAAVVAGEHVVPVAEFMPRTDGVGLLYAGRVHSLAGEPESG
                     KSLLAQAEVARVLAAGGSAVYIDGEDTPGNVVARLLAMGAPAEVLTGERFRYVRPEVS
                     PGVLSEAQAWQQLLAQPVDMVVIDGVTEFLGLAGASSKDGDDVTAWMRGVPRRIARET
                     GAAVVLIDHVTKDRDTRGRWAIGSQAKLAACDAAYIVEPKLPLGRGMRGLVVVRVAKD
                     RPGGVRPHAAMPWRASDRTAEVARVSVDSSDGEAIRVVVDPPAVGGESGEDDGPGVGH
                     SGGGSRLTGYMERLSKVLEASPEPLTTNLLTKDTDVMRGRPQYRSQALATLVAEGYVA
                     ATPGPGRSQLHRSVRSYREAQDPRSDQFDGGNHLSPAGGSEGGAAPVVPGSPSSTGEP
                     GNHLEGSGWVVPGTAGEPPGNHREPPTEDTVEDDQ"
     gene            complement(4456..4899)
                     /locus_tag="Krad_4703"
                     /db_xref="GeneID:5333478"
     CDS             complement(4456..4899)
                     /locus_tag="Krad_4703"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355392.1"
                     /db_xref="GI:152963959"
                     /db_xref="GeneID:5333478"
                     /translation="MMTADPTDPARTAWLDQLDALFREADAEAERELQHPRAEELQTP
                     PLWMVAALTAAGIAVASGQAQERWCAHVRGPGMLTTCAWGAHVYACRRPECETALQAL
                     PGARAECDQCHAPAVAGIGRVLYGPLAVLYRLCPSCLQRKTGARA"
     gene            complement(4896..5207)
                     /locus_tag="Krad_4704"
                     /db_xref="GeneID:5333475"
     CDS             complement(4896..5207)
                     /locus_tag="Krad_4704"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355393.1"
                     /db_xref="GI:152963960"
                     /db_xref="GeneID:5333475"
                     /translation="MSRRRRPVPTTASANATSTAPASTASVSTLAPPARFALLVTTWF
                     PEGHRRQRLLLSLAAAQRARDRALAKRHPVSITLVELAPVAAQDCEAALAEVTAAGAV
                     A"
     sig_peptide     complement(5130..5207)
                     /locus_tag="Krad_4704"
                     /product="hypothetical protein"
                     /note="Signal predicted by SignalP 3.0 HMM (Signal peptide
                     probability 0.995) with cleavage site probability 0.621 at
                     residue 26"
     gene            complement(5204..5461)
                     /locus_tag="Krad_4705"
                     /db_xref="GeneID:5333477"
     CDS             complement(5204..5461)
                     /locus_tag="Krad_4705"
                     /note="PFAM: helix-turn-helix domain protein"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain protein"
                     /protein_id="YP_001355394.1"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="GI:152963961"
                     /db_xref="GeneID:5333477"
                     /translation="MPSSVQTSPEAATSAEGPVRLRWDGIAARRAREGAGLSRETVAQ
                     YTGQSAGMLRRYERCEVQPRIDVAARMAAAYGVPLTDLMTA"
     gene            complement(5837..6964)
                     /locus_tag="Krad_4706"
                     /db_xref="GeneID:5333474"
     CDS             complement(5837..6964)
                     /locus_tag="Krad_4706"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355395.1"
                     /db_xref="GI:152963962"
                     /db_xref="GeneID:5333474"
                     /translation="MLATAHRSAAPSLQVQHGPRDHDLPTSPHAAGRLRRRRHAPAWW
                     RHVREVITAEAGRRDLREHLLAYAWLLAKSARGDGTTTLVRTKAADQLGLTERTVARL
                     RARLEALGLLVVLEHGSTPSTRGGHHPAAGQDGNRCAVYALTIPVDPADAPQQTSAEV
                     LPQNRILRNVTPPLSTERGNKITHARVRDTRIAVAERAATRRDDDLARRRLRRDGSPT
                     RGQTRTDQLLLAAKVRHRAQTLAEAEHLPWLAELLAVSTPWLASLLRQAGLLELTPDQ
                     VVYVVGHAPDGSLRTAATTPEHPVAVLRWRLKAWGQLIDAMGLERALAGHAAQQQRLE
                     AVRARRAAEAAERQTASAVLPPIAQHALAALREANARRRCS"
     gene            complement(7615..8187)
                     /locus_tag="Krad_4707"
                     /db_xref="GeneID:5333481"
     CDS             complement(7615..8187)
                     /locus_tag="Krad_4707"
                     /note="PFAM: Resolvase domain; Resolvase helix-turn-helix
                     domain protein
                     KEGG: art:Arth_4386 resolvase"
                     /codon_start=1
                     /transl_table=11
                     /product="Resolvase domain"
                     /protein_id="YP_001355396.1"
                     /db_xref="InterPro:IPR006118"
                     /db_xref="InterPro:IPR006119"
                     /db_xref="InterPro:IPR006120"
                     /db_xref="GI:152963963"
                     /db_xref="GeneID:5333481"
                     /translation="MTTLTTTGRLIGYARVSTGDQDAALQQDALVAAGCAQVLTDMAS
                     GALTSRPQLEVALQGMGPGDTLVVWRLDRLGRSLRHLLEVVDGLAARGVGFRSLTESI
                     DTTTATGRLVLHLFGALAEFERDLVRERTEAGLAAARSRGRRGGRPTVMTPAKIAAAR
                     AMLAGEAHSVRETAEALGVSRATLYRSLNN"
     gene            8435..8671
                     /locus_tag="Krad_4708"
                     /db_xref="GeneID:5333482"
     CDS             8435..8671
                     /locus_tag="Krad_4708"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355397.1"
                     /db_xref="GI:152963964"
                     /db_xref="GeneID:5333482"
                     /translation="MQNKITTAQNADRNDQRLVATMTKLAPAIARQLTRKASQRTPDR
                     VEVFVTLLCDRLRPGRENRLSVRDAWEASGLATR"
     gene            complement(9104..9484)
                     /locus_tag="Krad_4709"
                     /db_xref="GeneID:5333483"
     CDS             complement(9104..9484)
                     /locus_tag="Krad_4709"
                     /note="KEGG: ani:AN5649.2 hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355398.1"
                     /db_xref="GI:152963965"
                     /db_xref="GeneID:5333483"
                     /translation="MAKPAPKTALRKAPAAVHPVAPPAPAAALAGNDLQDPFLPGFDP
                     APSDAVDAAPAPESAPAAESVAEPVTSPAAPAGQPAAALPMFSVRMDPTLRRRVKRWA
                     AENDTTVQALTAAALSEYLERHDG"
     gene            complement(9484..10275)
                     /locus_tag="Krad_4710"
                     /db_xref="GeneID:5333468"
     CDS             complement(9484..10275)
                     /locus_tag="Krad_4710"
                     /note="PFAM: Cobyrinic acid ac-diamide synthase
                     KEGG: art:Arth_4176 cobyrinic acid a,c-diamide synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="Cobyrinic acid ac-diamide synthase"
                     /protein_id="YP_001355399.1"
                     /db_xref="InterPro:IPR002586"
                     /db_xref="GI:152963966"
                     /db_xref="GeneID:5333468"
                     /translation="MLTVAFTNQKGGVGKTSTVVGIAAALDRRGLRVLCIDLDPQADL
                     TQWLGLDPLDDVRNVNDAVYADTRGIAAEAIQHAGWGAGIDVIGSTLDLAERETDLSP
                     GSEFRLAKALDGLSGYDVVLIDCPPSIGRLVVLGFVAATHVVVVTEPSAASLRGVENV
                     LRTRDVVAEHYNRKLQLAGIVVNHQNRTTESALRVAEVAEVYGAAVWEPYVPARAVVA
                     AAMGAAASVADYGADGKPVAEVYDALAERVLALQTLSTPSTVEVS"
     gene            10406..10744
                     /locus_tag="Krad_4711"
                     /db_xref="GeneID:5333471"
     CDS             10406..10744
                     /locus_tag="Krad_4711"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355400.1"
                     /db_xref="GI:152963967"
                     /db_xref="GeneID:5333471"
                     /translation="MALPSLHRGPASPRIRQGPRQAATRRGPRAHHQWSPDLHSERSA
                     MSKRLPTPKFNTPDPEDRNPQVILGWWITLTAPVVAVVLHDTGAMTLQLAAGLALLGL
                     PLPGGDRPAT"
     gene            11044..11517
                     /locus_tag="Krad_4712"
                     /db_xref="GeneID:5333472"
     CDS             11044..11517
                     /locus_tag="Krad_4712"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355401.1"
                     /db_xref="GI:152963968"
                     /db_xref="GeneID:5333472"
                     /translation="MAVGTTVPVREAAASPSPHGDDANRHGLGPMTDDTDTDTEAVAV
                     KLLPTDPQDMTPPAVAWAKAVLAEVRTIPRARLQASARTSLTAVTWTLAAAADWLYTI
                     LPSLPPRSSRLWAQHLGMERPPEPQVLWTEGWTRRGPAAVPLWRTRRHDTTRRTR"
     gene            11684..12043
                     /locus_tag="Krad_4713"
                     /db_xref="GeneID:5333476"
     CDS             11684..12043
                     /locus_tag="Krad_4713"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355402.1"
                     /db_xref="GI:152963969"
                     /db_xref="GeneID:5333476"
                     /translation="MSKYLDHPGAEQENPGQRGVLGKLRGDQGPCTACFATPTWKGSH
                     MGISYDRRYPMSAQASILGALLILVVPVLIYLHPLMDPALAAVPAAIGFRLFWPRQGR
                     PRWGTGGAGDRRRRPLT"
     gene            complement(12078..12308)
                     /locus_tag="Krad_4714"
                     /db_xref="GeneID:5333473"
     CDS             complement(12078..12308)
                     /locus_tag="Krad_4714"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355403.1"
                     /db_xref="GI:152963970"
                     /db_xref="GeneID:5333473"
                     /translation="MNQRDAVADWWADADEPTRRRALRLAEDDLLPEDMQRGLAMAGV
                     TVIPLGRSGVDEGPLGYLQPDALVDFLAELRN"
     gene            complement(12446..12907)
                     /locus_tag="Krad_4715"
                     /db_xref="GeneID:5333470"
     CDS             complement(12446..12907)
                     /locus_tag="Krad_4715"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_001355404.1"
                     /db_xref="GI:152963971"
                     /db_xref="GeneID:5333470"
                     /translation="MVQVRAVVGEHGQALTADDLLRTNGAAGDRARAAVARLHALHAE
                     LETVRRVHLALFAYLTAGRDREVVPGTAATMTALARARVLWCPGFATAWPAWRRPLVP
                     PGTPEPASPWQGGPVQQLLTLVAHGSWTPTPQQVATAWLDALDAQDGAPAA"
ORIGIN      
        1 tgatggctgc tcacgggccc ggtcagcagg tcctcggcgt gctcggccag caggtgccgg
       61 gccagggtgc ccacctggtc ggtggcggcc accacgacgt tgcggtgttc ctcggcggcg
      121 gcgatgcgcc ggcgggcggc cagcaggtcg tcggcggcgt tggccggcac gtcctcgccg
      181 gccaacagcg cctgagcgcc ggcgtgcacc aaggcggcgg tgtcgatgcc cggcgtggtg
      241 gtcatggacg ccagctgcgc catgccgcgc tgccaggcgc gggtggcggt cagcaggtcg
      301 gtcggggcgg cgtcggccag gtgctcggcc accgcctgca gcgcggtggc ggtgtggcgg
      361 ctcacctgct gcggcaccgc gcgcatcgtc gcggtgggga tcggggcggg ggtggtctcg
      421 gtggtcatgg tgtctccagg tctcagagga cgatgccggt gtgatcgccg cgagggcggg
      481 gctcgggttc ccagggcttg gccggcgggc cctgcggcgg ggtggccagc tcgcgcagct
      541 gcgcggcgat ggcgtcctgg acgcgctgct gcagcgcctg cgcggcctgg ctggcggggt
      601 cgggcgtgac cgcctcggtg accgccgcag ccgccgagcg gatggcggcc tcggtcgccg
      661 ccatggtcgt ggggtccacc accgcgcggt tgcccggggg cagggcggcc accatcgcct
      721 cggcgtgggc gcgcacggcg gcggcacgct cagccccagg cccgtcctcg cggccggacg
      781 cgctgcgcat caccgccggc gccggcggca tgggcagtgg cgactggccc agggcctggc
      841 gcatcgcgtt caccttcatg gccaccaggt aggggtggtc ggggggcagt tcctgcggca
      901 tcagttctcc aggtagctgc tgagcgagat caccgaggcg tcgtcctcgg tgggggctgc
      961 ggtcggcagg tgccaccgca ggcgttcgcg cgccagggcg gacaggccca ggcggtcctc
     1021 cagggcgcgc agctcggcca tgcgcttggc accggcttca tcgccacgtg cgatggcggt
     1081 gcgcagcagg accacgcgca ccgtcaccgc caggtcggcg gcggggtccc actggctggc
     1141 catgggcgag gaccacagca gccagaactc ggccacggcg tccttgccgg cctcgcgcac
     1201 gacctcgggc acctgctggg gcctggacca gttcggcgcc gttcccagca ccggcagatc
     1261 ggtccacccg gccgggcggc ggtggctacg tgcgtcacgg ggcaacatgc gtgtgctctc
     1321 ctgcctgttc tcggtgttcc tgaacccctg ggggacctca gcagcgcgac cgcgcagaag
     1381 cccacccctg cgctggctgc gcccctcggg acctcgcctt gatgccccca cccgcccctg
     1441 tacgcccggc tgacgggccc gcggcacctc gccggtgtcc caggaccccg gcgaaccccg
     1501 agccctcaac gaggcgttca cgcgcgaccc ccggccccgg ccgagatggc gaaccggcga
     1561 gggcggcgag cacgggcagc cgcagcgcag cgcgagcaca ctccccggca gcggtcgggg
     1621 tcgcgcgggt cgatgcccaa cgcacgcaac gtcggcgccg gcaccgggtg cgcgatgacc
     1681 gcgacgcacg gtcccgagcc acagcggcag caggtggggt cgatggcgac cacggcctgc
     1741 agcaggcccg gctcgggcac ctgctggcga cggcggtaca ggttcactgg tcgtcctcca
     1801 cggtgtcctc ggtgggtggt tcccggtggt tcccgggtgg ttccccggcg gttcccggaa
     1861 ccacccagcc agagccctcc aggtggttcc ccggttcccc ggtactagac ggggaaccgg
     1921 gaaccaccgg ggcggcacca ccctcggacc cacctgcagg gctcaggtgg ttcccgccgt
     1981 cgaactggtc actgcgcggg tcctgcgcct cgcggtagct acgcaccgag cggtgcagct
     2041 gtgaacggcc ggggccgggg gtcgccgcca cgtagccctc ggccaccagg gtcgccaacg
     2101 cctggctgcg gtactggggc cgcccccgca tcacgtccgt gtccttggtg agcaggttcg
     2161 tggtcaaggg ttcggggctg gcctccagca ccttggacag tcgttccatg taccccgtca
     2221 gccgcgaccc gccaccgctg tggccgacgc cggggccgtc gtcctcgccg ctctcaccac
     2281 cgactgctgg cgggtccacc accacgcgga tggcctcgcc gtcgctggag tccaccgaga
     2341 cccgcgcgac ctcggcggtg cggtcgctgg cccgccacgg catcgccgcg tgcgggcgca
     2401 ccccgccggg gcggtccttg gccacgcgca ccaccaccag cccgcgcatc ccacgcccca
     2461 gcggcagctt gggttccacg atgtaggcgg cgtcgcaggc ggcgagcttg gcctggctgc
     2521 cgatggccca gcgcccccgg gtgtcgcggt ccttggtcac gtggtcgatc agcaccacgg
     2581 ccgcgccagt ctcgcgcgcg atgcgccggg gcaccccacg catccacgcg gtcacgtcgt
     2641 cgccgtcctt ggaactagcc ccggccaagc ccaggaactc cgtcaccccg tcgatcacca
     2701 ccatgtccac cggctgcgcc agcaactgct gccacgcctg cgcctcgctg agcaccccgg
     2761 ggctgacctc agggcgcacg tagcggaacc gttcacccgt cagcacctcg gccggggccc
     2821 ccatcgccag cagccgggcc acgacgttgc cgggggtgtc ctcaccgtcg atgtagaccg
     2881 cgctgccgcc ggcggccaac acccgggcga cctcggcctg ggccagcaag ctcttgccgc
     2941 tctcgggttc accggccagc gagtggaccc gcccggcgta cagcaacccc accccgtcgg
     3001 tacgcggcat gaactcggcc accggcacca cgtgctcgcc ggcgacgacc gccgccaggt
     3061 ccaccggcgc ccacgtagcg cgtacgggtt cgccgccgtc ctctccggcg tgcgggccgg
     3121 tgtcctcccc gctgtccagg ccggcgttct cgcggccacg ttcggcatcg gcggtcacgt
     3181 cgtggcggtg ctgcaggagt gcgaggggca gcgccgccgc cggcagcggt gaggatgcgc
     3241 ggctgccccg gcgctgcacg tggcgctcct gcagcaccgc cacgacgtgg gcggggatgc
     3301 cgaacgtggc cgcaccgggc accccgttca gcgccggctg cagcttgtgg cagaacgcgc
     3361 tgaggtcgcc gccgaacccg gcgaggtggg acagcagccg gggcacgttc aggcccaccc
     3421 cggtgggcag gtcggcgttg tccgaccagt tcacgaacac gtcgtgcccg tcgtgcccgc
     3481 tgtgacccga caccgggttg gacgggttgc ccggccggcg ccactgcagt tcgccggtgg
     3541 ggctctgggc caccgcggtc cagcccgcgg cctccaggac ctcgcgcacg ctgaggtgcg
     3601 cggcgagggt ctccaacagg ttggtgcccc cgccggtctc gtcggcgagg aagcgcccgg
     3661 tgttggtggt cggcgcgctg cgcgccgggg cgccgacgga gaacgccgac ggcggcgtcc
     3721 tggacaccga cacggggtgg cgggcgtcga ggtcggcgct ccactgctgg aggtgggcga
     3781 gggtgtagcg ggggccgtcg gccagcagga tgcgccgcag caccgggcgc cgcccgggct
     3841 tgcggctcac cgtccccgcg gcgccgagga cccgcgcgag gtcgtggggc ttggggtcgt
     3901 agacgaaccc ctgggcggcg aacccccgcg ccacgccctc cccgagccgg cgcagcagag
     3961 cagcgaccgc ggcgcggttg ccgtcgtcga tcagctcggg gtgctccagc aggaggtagg
     4021 ggtgctggcc gtggccgctg tcgaccagca gcgacggggg cggcaggacc tgggagaaca
     4081 gctgcgccag ctgttcgctg tcgcgcggca gcaccaggcc gtcttcgcgt tcgggggttt
     4141 cgtgcgccag cagggtgtcg ccgtcgaacc acgccccggg cagcaccgcc gaggcggtgt
     4201 caccgcctcg gccgcgctcg ggacgctgac gctgcgagca cacccgcaac cagacactgc
     4261 tggccgcact actccagctg gaggcgatgg cctcggcctg ctccgcggtg tccaggtgga
     4321 ccgtccacgg caccgcacgg tcggggaagg cacccgtcag cgagaccagg aaaccgggcg
     4381 gcaccaggct ctggacgtgc tgcaggaact gcgcaccatc gtgttgcggc aggtagctga
     4441 ccggctccac cgcgctcacg ccctggcccc cgtcttgcgc tgcaggcagc tggggcacag
     4501 ccggtagagc acggccagcg gcccgtagag cacccggccg atgccggcga cggcgggggc
     4561 gtggcactgg tcgcactcgg cccgggcgcc cggcagggcc tgcagggcgg tctcgcattc
     4621 ggggcggcgg caggcgtaga cgtgggcccc ccaggcgcag gtcgtgagca tcccggggcc
     4681 gcgcacgtgg gcgcaccacc gttcctgggc ctgcccgctc gccacggcga tgccggcggc
     4741 ggtcagggcg gcgaccatcc acagcggcgg ggtctgcagt tcctcggcgc gggggtgctg
     4801 cagttcacgc tcggcctcgg cgtcggcctc gcggaacagg gcgtccaact ggtccagcca
     4861 ggcggtacgc gcggggtcgg tcgggtcggc ggtcatcacg ccaccgcccc ggccgcggtg
     4921 acctcggcta gggctgcctc gcagtcctgc gcagcgaccg gggccagttc caccagggtg
     4981 atggagacgg ggtggcgctt ggccagggca cggtcgcggg cacgctgggc agccgccagc
     5041 gacagcagga ggcgctggcg gcggtggccc tcggggaacc aggtcgtcac cagcagcgcg
     5101 aaccgcgcgg gcggggcgag tgtggagacg ctggcggtgc tcgccggcgc ggtgctggtc
     5161 gcgttcgcac tggcggtggt cggcaccggg cggcgtcggc ggctcacgcg gtcatcaggt
     5221 cggtgagggg cacgccgtag gccgcggcca tgcgcgcggc cacgtcgatg cgcggctgga
     5281 cctcgcaccg ttcgtagcgg cgcagcatcc cggccgactg gccggtgtac tgcgccacgg
     5341 tctcgcggga cagccccgcg ccctcgcggg cccggcgggc ggcgatgccg tcccagcgca
     5401 ggcgcacggg cccctcggcc gaggtggcgg cctcggggct ggtctggacg gacgacggca
     5461 cgacgacctc caccgttgat cgggacgacg acgcccggac aggcgccgtg cgcgcatcag
     5521 cccgccagcg gtggccccga ggggagatcg ccgagctagt cagggcgggg cgggacccac
     5581 gggtgcggtg cgcggcctcg cgccctgcac cgcacccgcc cctgacccac gcccatgcag
     5641 cgcgtgactg gacggtggca tgtagtcaca gaatgagcaa ccccgtctgg gcatgtaatc
     5701 cgttgcggga gaagcacata cgtgtgccag aaagattgat tacgttgcag cgcaaggagt
     5761 tcgcctgtgg ataacgtgct cacgattcgt tcaaattccc tgggacacaa cgcgtctggc
     5821 acacacatgt gattcgtcag gagcaccggc gccgggcgtt cgcctcgcgc agggcggcga
     5881 gggcgtgctg cgcgatgggg ggcaacaccg ccgaggcggt ctgccgctcg gcggcctcag
     5941 cggcacgccg agcgcgcacc gcctccaggc gctgctgctg cgccgcatgg ccggccaggg
     6001 cccgctccag ccccatggcg tcgatcagct gcccccacgc cttcaggcgc caacgcagga
     6061 ccgccacagg gtgctcgggg gtcgtcgcgg cggtgcgcag gctgccgtcc ggggcgtggc
     6121 ccacgacgta gaccacctgg tccggggtca gctccagcag gccggcctgg cgcagcaggc
     6181 tggccagcca cggcgtggag accgccagca gctcggccag ccagggcagg tgctcggcct
     6241 cggccagggt ctgcgcccgg tggcgcacct tggcggccag cagcagctga tcggtcctgg
     6301 tctggcctcg cgtcggtgat ccatcccggc gcagccgccg cctggccagg tcgtcgtccc
     6361 ggcgtgtcgc tgcacgttct gccactgcga tccgggtatc gcgcacccgc gcgtgggtga
     6421 tcttgttccc tctctctgta gagagagggg gggtgacatt tcgtagaatc ctgttctgcg
     6481 gcaacacctc tgcagaggtc tgctggggtg cgtcagcggg gtccaccggg atggtcaggg
     6541 cgtaaacggc gcagcggttg ccgtcctggc cggcggccgg gtggtgcccg ccccgggtgc
     6601 tgggggtgct gccgtgctcc aggacgacca gcagccccaa cgcctccagg cgggcgcgca
     6661 ggcgggccac ggtgcgctcg gtcaggccta gctggtcagc ggccttggtg cgcaccaggg
     6721 tcgtggtgcc gtcgccgcgt gcgctcttgg ccagcagcca ggcgtaggcc agcaggtgct
     6781 cgcgcaggtc gcggcgcccg gcctcggccg tgatgacctc acgcacgtgg cgccaccagg
     6841 ccggggcgtg ccggcgccgg cggaggcgcc cggcggcgtg cggcgaggtg ggcaggtcgt
     6901 ggtcgcgggg accgtgctgg acctggagcg agggggcggc gctgcggtgc gccgtggcga
     6961 gcacgtcagg cggccgtcag ccgtcccggc gaggtgtcgg tagggctcgg gggccccgtc
     7021 caggtgtcgt tccggccacg gaagcgtgtc agggacaccc tgacacgccg aggggggcgc
     7081 gtagttctcg cgccggcagg ggttccctgc ttactctggt cctgcaccgc tgctcccgag
     7141 gggctactcg tgagttgtgg aagggccctc gttgttgacg caacgggggc tcttggctgt
     7201 ccggggtcgg acaggtgccc tgaccctgcc cgcgatcacg cttgggacct acgcgacacg
     7261 ccgcacgtca gggcagggtg gtccaccacg acgaaggccc tggcgccggc tgcagtccgg
     7321 tcaccagggc ctcatcttat ttagctctaa aatactttat aacttccaga atttgggcaa
     7381 tcaattctgg tgaaactggc ccaatatgtt caatcgcttt aaggctcaat tgaaatgcca
     7441 tatagattag tagtagaaat acgccttcaa ttcccataat agttatcctt ttcgttagtt
     7501 gaattacatt attcctcggc caaaggagat tacatcttag cacgccgacc atgatcacgt
     7561 caagtccaag gaaagccaac gtgttgtgcc acaacgaatc tcgacgcctt taaatcaatt
     7621 gtttaaactg cgataaagcg tggcccgact gacccccagc gcctcggcgg tctcgcggac
     7681 gctgtgggcc tcgccggcga gcatcgcgcg ggcggcggcg atcttggctg gcgtcatcac
     7741 cgtgggtctg cccccgcgcc ggcctcggga ccgcgccgct gccagcccgg cctcggttcg
     7801 ctcacgcact aggtcgcgct cgaactcggc aagagcgcca aaaaggtgca gcaccagccg
     7861 gccggtggcc gtggtggtgt cgatggactc ggtgaggctg cggaagccca cgcctcgggc
     7921 ggccaggccg tccacgacct ccagcaggtg ccgcagcgac cgcccgaggc ggtccaggcg
     7981 ccagaccacc agggtgtccc ccgggcccat cccttgcagc gcgacctcca gctgtggccg
     8041 gctggtcagc gcccccgacg ccatgtcggt cagcacctgg gcgcagccag cggctaccag
     8101 ggcgtcctgc tgcagggcgg catcctggtc gccggtgctt acccgggcgt agccgatcag
     8161 ccggccggtg gtcgtcagcg tcgtcatgag cgcggaccct gccacctgtc tcagacgccg
     8221 tggccgtcaa cgcagcgttg cggacacggg ttgtgcgacg gcgtggcgcg gtggccgggc
     8281 gcgtcgcacc agttgtctcg caaccgagcg gttctgagac gcccggaagg gcccatgtga
     8341 ctgccacagc cggggcaccc attcaccgtg cagctggcgg tcggcagcag gtcggcccca
     8401 gcacgacacc ggatacctac cgagaggcac gaccatgcag aacaagatca cgaccgcgca
     8461 gaacgccgac cgcaacgacc agcgactggt ggccaccatg accaagctgg cgccggccat
     8521 cgcgcgccag ctgacccgca aggccagcca gcgcaccccc gaccgcgtgg aggtgttcgt
     8581 gacgctgctg tgcgaccgcc tgcgccctgg ccgcgagaac cggctgagcg tgcgggatgc
     8641 gtgggaggcc agcggcctgg cgacccgcta ggccaggccg caccgccgcc ggccgccggc
     8701 cgccgcagtc gctcaccacg gctgcggcgg cggggcgccg ggcatgatgc cgtcatgccc
     8761 gtgacctacc gtgccgctgc ggtgcgcccg aggtcgcccc ggccaacctg cgccagacgg
     8821 caccctgacc tcatgcagca acgtcggctg aacatgggcc ccaagcgcaa ggcgtggggc
     8881 gtggagcggg tcaccatccg tggccgggac cgtggcctgg agtaccgcca gcgggtgatg
     8941 cgagtacgca tgcccggctg gggcagctgg ctcaacatcc cgctggggcg tcgtgtgtgg
     9001 gtgcacgact acacccacct aggacctggc ggtctctgac ctgcatgttt acatgcatac
     9061 atgccatctt gctgacctgc aggcatgtct gcatgcagga atgtcagccg tcgtggcgct
     9121 ctaggtactc gctcagcgcg gcggcggtca gggcctgcac ggtggtgtcg ttctcggccg
     9181 cccaccgctt gacccgccgg cgcagcgtgg ggtccatgcg cacgctgaac atgggcaacg
     9241 ccgccgccgg ctgacctgcc ggcgcagccg ggctggtgac gggctcggcc accgactcgg
     9301 cagccggcgc ggactcaggt gcaggcgcgg cgtcaacggc atccgagggc gcggggtcga
     9361 acccgggcag gaacgggtcc tgcaggtcat taccggccag cgctgctgcc ggcgccggcg
     9421 gtgcgacggg gtgcacagcg gccggggcct tgcgcagcgc ggtcttgggg gcgggcttgg
     9481 ccatcaggac acctccacgg tgctcggggt gctcagggtc tgcagggcca ggacgcgctc
     9541 ggccagggcg tcgtagacct cggccacggg cttgccgtcc gcgccgtagt cagccaccga
     9601 ggcggcagcg cccatcgccg ccgccaccac cgcgcgggcg ggcacgtagg gctcccacac
     9661 ggccgcgccg tagacctcgg ccacctcggc cacgcgcagc gccgactcgg tggtgcggtt
     9721 ctggtggttg acgacgatgc cggccagctg cagcttgcgg ttgtagtgct cggccaccac
     9781 gtcccgggtg cgcaggacgt tctccacccc gcgcaggctc gccgccgagg gctcggtgac
     9841 gaccaccacg tgggtggcgg ccacgaaccc caagacgacc agccggccaa tactcggagg
     9901 gcagtcgatc agcactacgt cgtagccgct gagcccgtcc agggccttgg ccaggcggaa
     9961 ctcgctgccg ggggacaggt cggtctcgcg ctcggccagg tccagcgtgg agccgattac
    10021 gtcgatgccc gcaccccagc cggcgtgctg gatggcctcg gcggcgatgc ctcgggtgtc
    10081 ggcgtacacc gcgtcgttga cgttgcgcac gtcgtccagc gggtccaggc cgagccactg
    10141 cgtcaggtcg gcctgcggat ccaggtcgat gcagagcacc cgcaggcccc ggcggtccag
    10201 ggcggcggcg atgccgacga cggtggaggt cttgcccacc ccgcccttct ggttagtgaa
    10261 cgcgacggtc agcatgtcta catacctaca tgtctacatg ttggcatgca aggacatcga
    10321 cagcgcgccg atctggtggt gcgacacgcc gcacttcaat cacgttgcgt gagaacaggt
    10381 cacggagggt ttccatctcg ccggtttggc tctaccgtca ctgcatcgag ggccagccag
    10441 tccccggata aggcaagggc cccgacaggc ggcaacccgt cgaggcccaa gagcacatca
    10501 ccagtggtcg ccagatctgc actcggaaag gtccgccatg tctaagcgtc tccccacccc
    10561 caagttcaac acgcccgacc cggaagaccg caacccccaa gtcatcctcg gttggtggat
    10621 cacgctgacc gctcccgtcg tggcggtggt cctccacgac accggagcca tgactctgca
    10681 gctggccgcc ggcctggcac tgctggggct tcctctcccc ggcggcgacc gaccggcgac
    10741 ctgacaggta cttcatcacc gaggtcggac actggccggc gtacagcagc ccgctgcgcg
    10801 ccggccaggc gtcgtcatga tgaaggaccc acccggccgc gccgatcatc caggggtgag
    10861 cacgaccacc cccgccggcg cgaccagcca acgcgcccga taggcccgca cggcggtcac
    10921 ggcggtcacg gcggtcacgg cggtcacggc ggtcacggcg tcgcggcacg gtcagccgtg
    10981 gaccgcgacc gaggacgtcg aactggccgc ctgcgtcaat gacgacgacc tggaggcgtt
    11041 tgcgtggcgg tggggacgac ggttcctgtc cgtgaagcag cggcgtcgcc gtccccgcac
    11101 ggggacgacg cgaaccggca cgggctgggt ccgatgaccg acgacaccga caccgacacc
    11161 gaggccgtgg cggtcaagct gctgccgacc gatccccaag acatgacccc gccggcagtg
    11221 gcctgggcca aggcggtgct ggcggaagtg cggaccatcc cgcgtgcgcg gctgcaggca
    11281 tcggcgcgta catcgctgac ggcggtgacg tggaccctgg ccgcagcggc agactggctg
    11341 tacacgatcc tgccgagttt gccgccgcgg tcctcgcggc tctgggcaca gcatttgggg
    11401 atggaacggc ccccggaacc ccaggtgttg tggactgagg ggtggacaag gcggggaccg
    11461 gctgccgtcc ccctgtggag gacacgccga cacgacacga cacgccgaac acgctgagtc
    11521 acgaccactg acgacgggtg gccgccaggg gggtgacgac ggagcagaac cgcaggtcag
    11581 gggttttgca cgctcagatg gcgtgcggcg gagtccgatg cgtgaatgac attcttgtca
    11641 cacaccatct tgtgccggtt ttccacacga ccccgtaagg gtagtgtcca agtacctgga
    11701 tcacccaggc gcggaacagg aaaaccccgg tcaacgcggc gtcctaggaa aactacgcgg
    11761 cgaccagggt ccctgtactg cttgcttcgc aacacccaca tggaagggat cccacatggg
    11821 catctcgtac gaccgacgtt acccgatgtc cgctcaggcg tcgatcctgg gcgcgctgct
    11881 gattctggtg gtgccggtgc tgatctacct gcacccgctg atggacccgg ctctggctgc
    11941 cgtaccggcg gccatcgggt tccgcttgtt ctggcctcgc caggggcgtc cccggtgggg
    12001 gaccggcggg gctggtgatc gccgccggcg tccgctgacc tgacggattg ctgacccggg
    12061 cagaactctt gcccgggtca gttccgcagc tcagccagga agtccaccag cgcgtcgggc
    12121 tgcaggtagc ccaacgggcc ctcatccacc cctgagcgcc ccagcgggat cacggtgacg
    12181 ccggccatgg ccaggccgcg ctgcatgtcc tcgggcagca ggtcgtcctc ggccaggcgc
    12241 agggcccggc ggcgggtggg ttcgtcagcg tcggcccacc agtcggccac ggcgtcgcgt
    12301 tggttcacct gcccatcgtg gagcctgcgc gccggcgctg gtcggggtct ccagcaccct
    12361 ggccatccgg tccagctccc ggcaacggcg tcgcgggatc ggccgggctg gtgaggttga
    12421 cgccggcgcg caggcgttca ggggatcagg ccgccggggc gccgtcctgc gcgtccaggg
    12481 cgtccagcca ggcggtggcg acctgctgcg gcgtgggcgt ccacgacccg tgcgccacca
    12541 gcgtcagcaa ctgctggacg ggcccgccct gccaggggct ggccggttcc ggggtgcccg
    12601 ggggcaccag ggggcgccgc caggccggcc acgcggtggc gaacccgggg caccacagca
    12661 cccgggcccg ggccagcgcc gtcatcgtcg cggcggtgcc cggcaccacc tcccggtcgc
    12721 gcccggcggt caggtaggcg aacagggcca ggtgcacccg ccgcaccgtc tccagctcgg
    12781 cgtgcagggc gtgcaggcgg gccaccgccg cgcgggcccg gtcgccggcc gcgccgttgg
    12841 tgcgcagcag atcgtcggcg gtcagcgcct ggccgtgctc accgacgacg gcgcgcacct
    12901 ggaccatcag cgcgtcg
//
